Hao Yingge, a post-95 college student: Returning her ticket, she chose to face the virus.

  Xinhua News Agency, Zhengzhou, April 12th Title: Hao Yingge, a post-95 college student: Returning the ticket, she chose to face the virus directly.

  Xinhua News Agency reporter Zhai Zhuo

  During the Spring Festival this year, Hao Yingge, a post-95 college student in Henan Province, probably made the most difficult and firm decision in her life — — Refund the ticket

  Hao Yingge is a senior majoring in medical laboratory in Sanquan College of Xinxiang Medical College. In June last year, she was sent by the school to Wuhan Huada Medical Inspection Institute Co., Ltd. for an internship. Before the Spring Festival, she packed her luggage like other foreign employees in the company and prepared to take the train back to her hometown in Henan for the New Year.

  However, the sudden outbreak disrupted Hao Yingge’s plan. At that time, Wuhan Huada Medical Research Institute had just undertaken some nucleic acid detection work on Covid-19 samples. Hao Yingge hesitated when he saw the mobilization order for the war "epidemic" issued by the company.

  "I am a medical student, and the nucleic acid detection work in Covid-19 coincides with my major. It is my responsibility to stay." Hao Yingge said.

  When she carefully told her family about the decision, the other end of the phone was silent. For a long time, my father Hao Jinzhou said, "Stay if you want, but you must protect yourself. Anything happens, I’ll pick you up right away. "

  Since January 23, Hao Yingge has been dealing with the virus for more than two months. Hao Yingge once wrote such a passage on his mobile phone, "If some time ago was the day when recruits joined the army for training and exercises, then the last two months have been really on the battlefield ‘ Fight ’ . Every battle needs a group of soldiers, and I am honored to be a member of the anti-epidemic army. "

  Information input, nucleic acid extraction, gene amplification, result analysis … … The daily inspection work is complicated and boring, but Hao Yingge has completed every link very carefully. There has never been a mistake in the virus samples she handled. "I hope to be responsible for every sample and every patient."

  Hao Yingge said that in recent days, her life is a "two points and one line" between the laboratory and the dormitory. "At the busiest time, the laboratory tested an average of 8,000 samples per day, and 12,000 samples were tested on March 1." The continuous night shift has exhausted Hao Yingge to the extreme, but once a sample is put into storage, she will still arrive at the post immediately.

  Hao Yingge works in the laboratory (photo taken on March 1). Xinhua news agency

  During the daily inspection, Hao Yingge has to face the test of "ice and fire". "Our hands are operated in a safe cabinet. After a long time, our hands will become cold. At the same time, airtight isolation protective equipment often makes her feel sultry. "

  In order to reduce the wear and tear of protective clothing, Hao Yingge will try to reduce the number of times he goes in and out of the laboratory. Every time before entering the laboratory, she often doesn’t drink water. The longest working time is that she has been busy in the laboratory for 10 hours.

  Together with Hao Yingge, there are three other interns from Sanquan College: Li Yan, Gui Yunfei and Sun Yujie. "Gui Yunfei and I are responsible for the inspection work, and Li Yan and Sun Yujie are responsible for handling medical waste." During this time, the four young people cooperated with each other and cheered each other every day. "If you stay, you have to rush forward. We are all great."

  Hao Yingge made a gesture of "comparing the heart" during work (photo taken on March 2). Xinhua news agency

  When Hu Miao, executive vice president of the School of Medical Laboratory of Sanquan College, heard the stories of Hao Yingge and others, he specially held a live online broadcast for them. "Seeing the various concerns and greetings of the students on the screen of the mobile phone, I don’t want to mention how warm I am."

  "They are just interns or children. If they choose to leave, no one will blame them. However, with their persistence and dedication, they set an example for our teachers and students. " Hu Miao said.

  After the "unsealing" in Wuhan, Hao Yingge was filled with emotion. "I still remember that when the traffic in Wuhan resumed, I took a bus back to my dormitory in the morning and there was a traffic jam when I turned left." Hao Yingge said that the traffic was blocked, but her mood was relaxed. "Traffic jams mean more people, more cars, the city is recovering, and life is full of fireworks. This is also the goal that my comrades and I have been working hard for more than two months. "

  After the "unsealing" in Wuhan, Hao Yingge jumped up excitedly (photo taken on April 9). Xinhua news agency

  Hao Yingge said frankly that she never thought that her choice would gain so much attention and praise. "People around me, like me, just want to get sick people treated, and people who are not sick can feel at ease. I know that my strength is very small, but with more efforts, I can overcome the epidemic earlier. "

  The reporter asked her if she would be afraid to face the virus directly.

  "I’m not afraid. I just hope to win this tough battle as soon as possible and go home as soon as possible. I miss my parents!"

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Free for all! The conditional listing of China’s first Covid-19 vaccine injected confidence into the global victory over the epidemic.

On December 25th, the staff inspected the product packaging quality in the Covid-19 inactivated vaccine sub-packaging workshop of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff inspected the product packaging quality in the Covid-19 inactivated vaccine sub-packaging workshop of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff worked in the Covid-19 Inactivated Vaccine Sub-packaging Workshop of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, I photographed the products being packaged in the Covid-19 Inactivated Vaccine Sub-packaging Workshop of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff worked in the Covid-19 Inactivated Vaccine Sub-packaging Workshop of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff checked the information before shipment from the vaccine cold storage of China Biological Beijing Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff opened the delivery port from the vaccine cold storage of China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, a cold-chain truck loaded with inactivated Covid-19 vaccine departed from China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On December 25th, the staff conducted an artificial light inspection in the sub-packaging workshop of Covid-19 inactivated vaccine in China Institute of Biological Products of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On April 11th, the staff tested the samples of novel coronavirus inactivated vaccine in the quality inspection department of China Bio-COVID-19 Vaccine Production Base of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On April 10th, the staff cleaned the equipment in the inactivated vaccine production workshop in novel coronavirus, which has not been put into production in China Bio-COVID-19 Vaccine Production Base of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On April 10th, the staff took a group photo outside the delivery window of novel coronavirus inactivated vaccine production workshop in China Bio-COVID-19 vaccine production base of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

On April 12th, the first volunteer was inoculated with novel coronavirus inactivated vaccine developed by China Institute of Biological Products of Sinopharm Group in Wuzhi County Center for Disease Control and Prevention, Jiaozuo City, Henan Province.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua news agency

On June 23rd, the launching ceremony of the International Clinical Phase III of COVID-19 Inactivated Vaccine developed by Sinopharm Group China Biotech was held in the United Arab Emirates.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua news agency

On April 11th, the staff tested the samples of novel coronavirus inactivated vaccine in the quality inspection department of China Bio-COVID-19 Vaccine Production Base of Sinopharm Group.

China has taken a crucial step in fighting the COVID-19 epidemic! The joint prevention and control mechanism of the State Council was released on December 31st. The Covid-19 inactivated vaccine of Sinopharm Group China Bio has been approved for conditional marketing in National Medical Products Administration, and its protection effect meets the requirements of relevant standards of the World Health Organization and National Medical Products Administration, and will be provided free of charge for the whole people in the future.

The listing of Covid-19 vaccine in China injected confidence into the global victory over the epidemic and provided strong support for the vaccine to become a global public product.

Xinhua News Agency reporter Zhang Yuwei photo

Farmer’s Daily: Strategic Thinking of China’s Agricultural Development Going Global

  In 1995, China put forward the idea of "going out" in agriculture, and in 2007, the No.1 document of the Central Committee formally put forward the idea of "going out" in agriculture as a national strategy. In the past twenty years, China’s agricultural "going out" has experienced the development process of folk initiation and national strategy implementation, and has achieved good results, but also encountered some problems. To sum up, the main achievements are as follows: (1) the accelerated growth of foreign direct investment, the increasingly extensive and diversified investment areas, methods and industries, and the rapid accumulation of investment income and experience; The main problems are manifested in three levels. First, there is a lack of self-ability at the enterprise level, such as lack of international talents and lack of overseas management experience. Second, there are obstacles to the absence of national public services at the institutional policy level, such as mismatched domestic financing policies and incomplete implementation of investment agreements among some countries; Third, there are environmental risk challenges at the host country level. In order to develop China’s agriculture globally in the future, it is necessary to assess the situation, strategize, locate accurately, ensure the overall situation and plan systematically.

  First, size up the situation, and deeply analyze the strategic situation of China’s agricultural development going global.

  (A) The present stage is a period of great strategic opportunities for China’s agricultural development to go global.

  Judging that the present stage is a period of great strategic opportunities for China’s agricultural development to go global, it is based on the following three facts: First, China’s national strength has been rapidly improved, and it already has the national strength to plan agricultural development on a global scale. Second, the world’s undeveloped agricultural resources are still abundant, and there is still huge room for China’s agricultural development to go global. It is timely for China’s agricultural development to go global by making use of the world’s agricultural development potential, filling the regional gaps and bridging the gap in the industrial chain. Third, the rapid growth of agricultural enterprises in China and the mature development of agricultural technology have created the profound internal strength for China’s agriculture to go global. It is timely for China’s agricultural development to go global, with export-oriented leading agricultural industrialization enterprises as the master and advanced and applicable agricultural technologies as the sharp weapon.

  (B) The current world development trend is generally beneficial to the global development of China’s agriculture.

  Judging the world development trend is generally beneficial for China’s agricultural development to go global, based on the comprehensive evaluation of the following challenges and opportunities: First, although there are still downside risks in world development and the prices of bulk agricultural products are in a depression, the global economy is in a post-crisis recovery period, the global monetary policy is generally loose, developing countries such as China and India strengthen economic reforms, and Asian, European and African countries actively respond to the "One Belt, One Road" initiative advocated by China. The recovery of the world economy is expected, the demand for agricultural products will be further expanded, and China’s agricultural development will move towards a global economic environment. Second, China’s agricultural "going out" has increasingly highlighted the concepts of "pro-,sincerity, benefit, tolerance" and "harmony", emphasized common development and mutual benefit, helped the agricultural development of the host country, won the hearts of the people and gained friendship, and the international environment for China’s agricultural development to go global has become more and more favorable. Third, although the risks of overseas agricultural operations are prominent, the overseas investment of Chinese agricultural enterprises to the world is growing steadily, with an average annual growth rate of more than 20%. The strategic tools to deal with various risks are gradually enriched, and the ability to identify, deal with and control risks is also significantly enhanced.

  Second, strategize and reposition the strategic goal of China’s agricultural development going global.

  At present, the global economic development is getting better for a long time, the international pattern is profoundly adjusted, the risks are identifiable, avoidable, preventable and controllable, and the international environment is generally favorable. Going global is a major choice for China’s agricultural development in the new period. We should strategize, accurately position, clearly define the goals and develop with the trend.

  First of all, we should establish the concept of "harmonious development", adhere to the motto of "pro-,sincerity, benefit and tolerance", and realize the win-win cooperation between China’s agriculture and the agricultural development of the host country. Secondly, we should clearly set the following goals: expand the development space of China’s agriculture, and enhance the global competitiveness, resource allocation, market control and international influence of China’s agriculture. Third, it is necessary to make clear the main body of China’s agricultural development going global, with large multinational agricultural enterprises dominated by China capital as the core body, small and medium-sized overseas investment agricultural enterprises actively participating in the global agricultural market as beneficial participants, relevant financial institutions, intermediaries and think tanks as the providers of core services, and government departments as the providers of key policies and public services. Finally, we should carry out the following ideas: consider and comprehensively apply the two international and domestic markets, two resources and two types of rules, actively implement the deployment of the "Belt and Road Initiative", accelerate the implementation of agricultural "going out", lay out the global agricultural industrial chain, build a number of key multinational agricultural enterprises, deeply integrate and control the key links and major value-added nodes of the global agricultural industrial chain, and build an efficient and sustainable global agricultural product supply and demand coordination network and a global allocation network of agricultural science and technology and resources.

  Third, make sure of the overall situation and systematically plan the strategic countermeasures for China’s agricultural development to go global

  (1) Strengthen strategic planning and support at the national level.

  It is a strategic choice at the national level for agricultural development to go global. It is necessary to make strategic planning, strengthen state support, carry out long-term strategic planning and implementation, and continuously strengthen macro guidance and service capabilities for agriculture to go global. The strategic deployment of China’s agricultural development going global should obey and serve the overall situation of the country’s development, coordinate and promote each other with the country’s diplomatic strategy, foreign investment strategy and foreign aid strategy, and realize the national interests to the greatest extent. Strategic planning should pay attention to gradual progress and divide strategic development stages. At the present stage, we should focus on developing stable agricultural products trade and providing agricultural assistance to developing countries. In the medium term, we should focus on overseas agricultural investment and international agricultural cooperation. In the long term, we should aim at building large-scale multinational agricultural enterprises, building a global agricultural product supply and demand adjustment network and an agricultural science and technology and resource allocation network.

  (B) to strengthen the cultivation of large multinational agricultural enterprises

  Multinational agricultural enterprises are the key subjects to enhance the global competitiveness, resource allocation, market control and international influence of China’s agriculture. Encourage all kinds of enterprises to increase overseas agricultural investment; As soon as possible, select a group of multinational agricultural enterprises with a certain scale, good development foundation, experience and foundation in foreign agricultural investment and development, strong economic strength and sufficient reserves of talents, especially international management talents, to give key support; We will build a group of powerful international agricultural enterprises that can operate flexibly and develop for a long time in the international agricultural industrial chain and international agricultural products market, compete with the four international agricultural enterprises of ABCD on the same stage, and have the status of China.

  (3) Deepening and expanding international cooperation in agriculture.

  Actively implement the "Belt and Road Initiative" and strengthen agricultural trade and agricultural economic and trade cooperation between China and countries along the "Belt and Road"; Implement the development concept of "harmony", focus on strengthening agricultural assistance and cooperative development of agricultural resources in developing countries or regions, and strive to improve the self-sufficiency and export supply capacity of agricultural products in developing countries; Strengthen close trade and investment cooperation with developed countries with rich agricultural resources, actively participate in their comprehensive agricultural development and global supply chain construction, and increase the effective supply of global agricultural products through multiple channels.

  (D) Layout of the global agricultural industrial chain

  From the perspective of the layout of the whole industrial chain, we should make reasonable arrangements in agricultural scientific research, agricultural research and development, production, processing, logistics, warehousing and sales, and make long-term plans to form the control ability of the whole industrial chain. Can be distributed to agricultural production related fields, provide technical training and services for local producers, and exchange technology and services for products and markets; Extend to the field of agricultural products processing to realize the value-added of agricultural products; Extend to infrastructure construction and lay out the logistics system of agricultural products transportation. The government should actively support Chinese agricultural enterprises to lay out key nodes in the global agricultural industrial chain, and form a diversified win-win situation with resource development and cooperation in the whole agricultural industrial chain as the core. Guide and support agricultural enterprises to tilt towards capital and technology-intensive industries such as processing, logistics, warehousing and docks, as well as key areas with high technology content such as research and development, improve the level of agricultural foreign investment, and continuously optimize the investment structure.

  (Author: Institute of Agricultural Economics and Development, Chinese Academy of Agricultural Sciences)

Emergency weight loss after the holiday? Nutrition experts talk to you about how harmful it is to your health not to eat on time.

Unconsciously, the Spring Festival holiday has ended, and many people have returned or are on their way back. Are you ready to start the work mode? What should I pay attention to before and after returning? What adjustments are needed to start work, diet, work and rest after the holiday?

After the Spring Festival holiday, many people set foot on the return journey. What should they pay attention to before, during and after the trip? After the long vacation, some people may have symptoms such as sleep disorder, anxiety and depression. How to alleviate and deal with "holiday syndrome"? A picture to understand.

Is it difficult for you to eat on time? Rushing to work and class in the morning, giving up breakfast after breakfast; Working overtime until late at night, you can only fill your stomach with snacks and supper. Even in order to lose weight, eating one less meal every day is designated as a personalized "rule" for eating.

Adults also need to get these nine vaccines.

Original Tencent medical code 

Never think that "vaccination is a child’s business". Even if you are an adult, it is very important to vaccinate in time & it is very important to replenish the vaccine that was missed before.

According to the report of the Centers for Disease Control and Prevention (CDC), 50,000 to 90,000 American adults die of vaccine-preventable diseases every year, such as pneumococcal diseases, influenza and hepatitis [1], and this statistic does not count cervical cancer caused by HPV (more than 5,000 people died of cervical cancer in the United States in 2018 [2]).

In this article, we have summarized 9 vaccines that adults need to consider:

Influenza vaccine: suitable for children and adults over 6 months old.

Herpes zoster vaccine: suitable for people over 50 years old.

23-valent pneumococcal polysaccharide vaccine: recommended for people with special health conditions over 2 years old and the elderly.

HPV (human papillomavirus) vaccine: suitable for all women aged 9-45.

Hepatitis A vaccine, hepatitis B vaccine and hepatitis E vaccine: Adults should also be vaccinated in time.

Chickenpox vaccine, measles, rubella and mumps vaccine: special circumstances, protecting adults.

If you don’t want to read the text, you can directly drop it down to the end of the article. We have sorted out the suitable vaccination population and vaccination methods of these nine vaccines in detail, and summarized them into a table for you to save to your mobile phone for comparison.

Many people misunderstand the lethality of the flu and think that the flu is just like a cold.

In fact, influenza is a very dangerous respiratory infectious disease.

Influenza can cause 290,000 ~ 650,000 respiratory disease-related deaths worldwide every year [3].

Maybe you will think, "I’m an adult and I’m in good health, so I don’t have to fight."

But unfortunately, the flu is a disease that the whole population is susceptible to. Even if they are not sick, adults are running around every day, and it is easy to bring the flu virus back to the elderly or children at home.

Therefore, people of all ages over 6 months old are advised to complete influenza vaccination in autumn and winter every year, preferably before the end of October [3].

(Long press the picture to save it to the phone)

The pathogen of herpes zoster is called varicella-zoster virus (VZV), which is a neurovirus.

People who have experienced the onset of herpes zoster, the biggest feeling is "pain"-pain like knife cutting, fire and electric shock.

Many people even say that it is comparable to childbirth pain and cancer pain. In fact, the pain of herpes zoster can also lead to suicide [4].

As long as you have been infected before (such as chicken pox when you were a child), the virus may lurk in the body for a long time. Once your immunity drops, it will come out and "mess up", leading to herpes zoster.

There is no specific treatment for this disease at present, and vaccination is the most effective way to prevent it [5].

Therefore, it is recommended that people aged 50 and above should be vaccinated against herpes zoster as much as possible.

(Long press the picture to save it to the phone)

Don’t think that "pneumonia is nothing to be afraid of". In fact, in addition to "pneumonia", Streptococcus pneumoniae is an important pathogen causing meningitis, otitis media, bacteremia and other infections, and it is also the main cause of community-acquired pneumonia.

About 1 million people worldwide die of pneumococcal pneumonia every year, and the mortality rate among the elderly and high-risk groups is as high as 30%~40%[6].

Vaccination with 23-valent pneumococcal polysaccharide vaccine can effectively prevent 23 common Streptococcus pneumoniae infections that lead to invasive diseases.

The elderly aged 60 and over, as well as the special population over 2 years old, are recommended to be vaccinated with 23 valent pneumococcal polysaccharide vaccine.

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Studies have shown that 99.7% of cervical cancer is related to HPV infection [7].

At present, there are three kinds of HPV vaccines on the market, 2-valent, 4-valent and 9-valent. Many people subconsciously think that the 9-valent vaccine is the best. In fact, within the allowable age, the sooner you get HPV vaccine, the better. It is best to get it before you have sexual experience.

If there is a shortage of 9-valent vaccine in your area and it is difficult to make an appointment, you don’t have to force it to be 9-valent.

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It has been more than 40 years since the immunization program in China, during which it has undergone several changes: the immunization program vaccine has expanded from 4 to 14, and the preventable infectious diseases have expanded from 6 to 15.

This means that from the current standards, some adults born earlier may miss some vaccines.

You can look for your own vaccination registration book to check the relevant information, or ask your parents about their own vaccination. If you can’t remember whether you have been vaccinated, you can treat it as "not vaccinated".

If you have not been vaccinated with the following vaccines, you need to consider replanting.

Hepatitis A, B and E vaccine

China is a big country with hepatitis. Viral hepatitis with great harm mainly includes:

Hepatitis A and hepatitis E transmitted through digestive tract, and hepatitis B and hepatitis C transmitted through blood, mother and child [8].

1. Hepatitis A

Hepatitis A vaccine was only included in the immunization program in 2008, so many adults have not been vaccinated.

Although hepatitis A has been considered to be well controlled, in recent years, the incidence group of hepatitis A in China is mainly adults. Take Liaoning as an example, the local incidence is mainly adults. The vaccination target of adult hepatitis A vaccine is ≥16 years old, and children are vaccinated at the age of 12 months to 15 months.

2. Hepatitis B

Hepatitis B, which makes many people turn pale, has been effectively controlled in recent years, but it is estimated that the number of patients still exceeds 84 million, and in 2018, more than 90% of hepatitis B virus infected people are adults over 20 years old [9].

What needs to be vigilant is that hepatitis B may also transmit the virus to children through mother-to-child transmission.

3. Hepatitis E

Hepatitis E may be very strange to many people, but in fact, there are more than 28,000 cases in China, even more than hepatitis A [10].

Moreover, few people know that hepatitis E, like hepatitis A, is transmitted through the digestive tract, and even less people know that hepatitis E can be prevented by vaccines.

Therefore, if you have never been vaccinated with these three vaccines, you should complete the vaccination as soon as possible according to your own situation.

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Varicella vaccine

Many people think that chickenpox is a disease that only children get. In fact, adults occasionally get sick, and the risk of complications and death of adults with chickenpox is higher than that of children [12].

Chickenpox virus is very easy to spread in a confined space, so it is recommended to vaccinate teachers, white-collar workers, pregnant women and people who may have close contact with chickenpox patients.

Anyone who has never had chickenpox, or who has only had one shot in the past, can be vaccinated or replanted.

(Long press the picture to save it to the phone)

MMR vaccine

The full name of this vaccine is "live attenuated measles, mumps and rubella vaccine", which can be abbreviated as "MMR vaccine".

The measles-mumps vaccine can stimulate the body to produce immunity to measles virus, mumps virus and rubella virus at the same time, thus preventing measles, mumps and rubella.

All three viruses can spread through droplets and are highly contagious.

Moreover, if a woman is infected with rubella during pregnancy, it may lead to congenital rubella syndrome in the fetus, resulting in irreversible consequences such as abortion and congenital malformation of the fetus [13].

In China, measles vaccine was mainly covered in the early years, and it was not until 2007 that measles vaccine was fully covered.

Therefore, most people born before 2007 suggest re-vaccination.

(Long press the picture to save it to the phone)

Finally, we have summarized the nine vaccination methods mentioned in this article for you in the following table.

(Long press the picture to save it to the phone)

references

[1]Reid KC, Grizzard TA, Poland GA. Adult immunizations: recommendations for practice. Mayo Clin Proc. 1999 Apr; 74(4):377-84. doi: 10.4065/74.4.377. PMID: 10221468.

[2]HPV Information Centre. United States of America Human Papillomavirus and Related Cancers, Fact Sheet 2018.

[3] China Center for Disease Control and Prevention, Influenza Vaccine Working Group of National Immunization Planning Technology Working Group. Technical Guide for Influenza Vaccination in China (2020-2021).

[4]Chidiac C, Bruxelle J, Daures JP, Hoang-Xuan T, Morel P, Leplège A, Hasnaoui A El, de Labareyre C. Characteristics of patients with herpes zoster on presentation to practitioners in France. Clin Infect Dis. 2001; 33:62–69.

[5] Herpes Zoster Expert Consensus Working Group of Dermatologists Branch of Chinese Medical Association. Herpes Zoster Expert Consensus in China. Chinese Journal of Dermatology 2018; 51(6): 403-8.

Chinese Preventive Medicine Association and Vaccine and Immunity Branch of Chinese Preventive Medicine Association. Expert Consensus on Immunoprophylaxis of Pneumococcal Diseases (2017 Edition) [J]. Chinese Journal of Preventive Medicine .2018,19 (3): 161-191.

[7]Arbyn M, Weiderpass E, Bruni L, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020; 8(2):e191––e203.

[8] National Health and Family Planning Commission of the People’s Republic of China. China Viral Hepatitis Prevention and Control Plan (2017-2020) [J]. China Journal of Viral Diseases, 2018.

[9]Wang H, Men P, Xiao Y, et al. Hepatitis B infection in the general population of China: a systematic review and meta-analysis. BMC Infect Dis. 2019; 19(1):811. Published 2019 Sep 18.

[10] Brief introduction of epidemic situation of Class A, B and C infectious diseases in China in December 2020 [J]. Disease Surveillance, 2021,36(01):1.

[11]Nelson NP, Weng MK, Hofmeister MG, Moore KL, Doshani M, Kamili S, Koneru A, Haber P, Hagan L, Romero JR, Schillie S, Harris AM. Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020. MMWR Recomm Rep. 2020 Jul 3; 69(5):1-38.

[12]Meyer, Pamela, A, et al. Varicella Mortality: Trends before Vaccine Licensure in the United States, 1970-1994.[J]. Journal of Infectious Diseases, 2000.

[13]Gary s. Marshall. Translated by Zhou Zumu. Vaccine Manual: A Practical Guide for Clinicians [M]. 4th Edition. Beijing: Peking University Medical Press, 2014.

Read the original text

320 kinds of Chinese roses were planted at the door of a florist’s house.

  Residents take photos and smell the fragrance among the rose flowers. Reporter Wang Liting photo

  Longsha Gem, Juliet, Royal Rouge, Eve Wine Cellar … … In front of an open courtyard in Huilong Garden Community, Houhu Street, Jiang ‘an District, 320 kinds of Chinese roses compete for beauty. On the morning of the 13th, residents shuttled among the rose flowers to take photos and smell the fragrance, as if they were in a small rose garden. In the richness and profusion of flowers, the neighborhood relationship in the community is also more harmonious.

  She is like collecting stamps.

  Collect 320 kinds of Chinese roses

  The reporter walked into the rose garden along the stone road, and the mixed flowers came to my face. Vines, shrubs and miniature roses came into view, with flowers and fragrance.

  "I am 47 years old. After my daughter went to college in 2020, I began to grow Chinese roses." Chen Ting introduced, "There are not only many varieties of roses, but also a long flowering period, which is very suitable for flower arrangement, so I began to plant roses."

  "I tried to plant 20 pots at first, and the results were very good, which gave me confidence." Chen Ting told reporters that she often watches flowers growing videos online, learns how to grow Chinese roses, and becomes more and more skilled in flower growing technology. Every time the nursery grows new roses, she always buys a few. "This feeling is like collecting stamps, more and more. Later, I couldn’t stop, and before I know it, there were 320 varieties."

  Only one plant is left for each variety, and the rest are given to friends. This is Chen Ting’s principle of raising Chinese rose flowers. "I like to try new varieties and want to see the difference between new varieties and classic varieties." Chen Ting said that due to the limited space, the remaining roses were carefully screened.

  "It is hot in Leng Xia in winter and short in spring. European and European varieties such as juice balcony, parade and Miranda are very suitable for planting here." Chen Ting introduced that different varieties of Chinese rose have different requirements for light and temperature, and they have to buy them for trial planting to know whether they are suitable for Wuhan’s climate. In daily observation, she has summed up the rose varieties that perform better and have good skin and good nutrition under the climatic conditions in Wuhan. "I often share my planting experience and experience with flower friends, hoping to make them take fewer detours in the process of planting roses."

  Watering, fertilizing, spraying, pruning, cleaning yellow leaves and pulling branches, Chen Ting works in the garden for at least 6 hours every day. After a long period of work, Chen Ting’s arms were covered with scratches of different lengths. "There are many thorns in the rose, and it is common for the arm to be scratched." With a photosensitive skin disease, she often relapses dermatitis, but she is still enthusiastic about raising flowers.

  Residents and properties

  Help manage the "Rose Garden"

  "When the flowers are in full bloom, she will invite us to enjoy the flowers and often cut them for us." Resident Zhang Ping said that with this garden, neighbors often walk around, enjoy flowers, walk and take photos, and the neighborhood relationship is more harmonious. "We will also bring friends to enjoy the flowers, and residents in the nearby community will come to punch in."

  During the flower viewing, Chen Ting will explain the varieties and characteristics of flowers. "She is a flower grower in our community, and we often turn to her when we are confused in the process of growing flowers ‘ Learn from the scriptures ’ 。” Resident Zhou Cuiping told reporters that flower friends usually go to the flower and bird market to choose flowers and see flowers.

  "I have only moved to the community for two years. I have met many neighbors through raising flowers and made many flower friends." Chen Ting recalled that at the end of 2021, Tan Heqing, the master gardener of the property, and the community flower friends spontaneously came to help prune the Chinese rose in winter. "The task of pruning and clearing the garden originally took two weeks, but it was all completed in two days."

  Chen Ting named the garden "Ian’s Rose Garden", symbolizing beauty and happiness. "I feel very comfortable enjoying flowers, drinking tea and chatting with flower friends in the garden on weekdays."

  Flowers bloom in the garden all the year round. Chen Ting’s enthusiasm also gained a lot of warmth by sending cut flowers every day and cutting branches in winter. The warm greeting when we meet, the flower friends who accompany us to chat when we take care of the garden, and the homemade sauerkraut presented by the neighborhood & HELIP; … Every little bit of daily life promotes the feelings between neighbors a little bit.

  "The beauty of the garden needs to be discovered and appreciated by everyone." Chen Ting said that in the future, she intends to continue to introduce new varieties and improve the scenery of the garden, so that neighbors who also love life can have a more comfortable and beautiful viewing experience.

  Reporter Wang Liting Correspondent Yu Wei Gu Wenjia

Domestic films grow in transformation.

During the Spring Festival this year, there were two war films in the film market, which triggered a movie-watching craze. The Battle at Lake Changjin’s sequel "Watergate Bridge of Changjin Lake" is based on large and medium materials, showing the "panorama" of the war; Sniper sees the big picture in a small way, which is more like a local "close-up" of the battle. The same theme of war, choosing the same schedule for release, all showed good box office appeal and word-of-mouth influence, breaking the previous market pattern of leading comedy films in the Spring Festival.

  The theme of war has always been an important theme in film creation. In the film history of China, there have been many creative upsurge of war theme, and a number of well-known works have been born. However, for some time, domestic war films have fallen into a creative bottleneck. Some of them are full of bullets and gunfire, but they make people sleepy. There are also obvious traces of preaching, lacking the power to penetrate the hearts of the people and being "left out" by the market. From the "big" of The Battle at Lake Changjin series to the "small" of Sniper, what kind of transformation has taken place in domestic war films?

  War movies are getting better and better, which is inseparable from the improvement of the film industry in China. The level of film industry is reflected in the typed creation, scientific and systematic production management and the application of new technologies. The creative experience of The Battle at Lake Changjin series shows that the same type of film can follow certain creative rules from script to production according to certain creative standards, and constantly replicate successful experiences to ensure sustainable production. The combination of technology and art is also an important standard of film industrialization. The Battle at Lake Changjin series created a breathtaking audio-visual experience for the audience with the help of high technology, and more than 90% of post-production and special effects technology were completed in China. At present, under the impact of online media, movies need to move towards a higher level of production, and movie audiences hope to get a completely different experience from other audio-visual platforms in the cinema. These changes urgently require filmmakers to lead the development of the industry with scientific and technological innovation. With the further improvement of film technology research and development capabilities, the unique charm of the big screen will further bloom.

  War movies are getting better and better, which is inseparable from the improvement of China’s storytelling ability. Nowadays, war movies pay more and more attention to telling short stories in the big scene. It can not only "get both the big and the small", but also "see the small and view the big", which not only has a panoramic expression of the war process, but also vividly depicts the ordinary soldier. From this point of view, although there is no grand scene in Sniper, its characterization is deeply rooted in people’s hearts. In particular, the use of dialects, with mild comedy to describe the tragic core, so that one by one amiable and respectable image of China soldiers leap onto the screen. The cultural attribute of the film determines that it must bear the national spiritual and cultural value. Therefore, film creation should not only pursue the shock of the scene, but also the shock of the soul. When the technical means that directors can use are more and more advanced, they should also settle down and think about what kind of art form to use to recall the bonfire years and pay tribute to the "most lovely person".

  Domestic films should not only base themselves on the domestic market, but also open their international horizons. What is worthy of recognition is that at present, while the domestic war films are promoting the main theme, the theme is no longer single, and the relationship between war and peace, war and people is deeply considered. Film art is a universal language and one of the best carriers to spread the story of China. China’s films still need to expand the breadth and depth of themes, strengthen international exchanges and cooperation, find the code of human empathy, and let the story of China really go to the world.

  The Battle at Lake Changjin series and Sniper show us that war themes have a broad creative space. By February 9, 2022, the total box office (including pre-sale) of national cinema films exceeded 10 billion yuan, which shows the consumption potential of the film market. It is expected that China films will grow in the process of transformation, and achieve a double harvest of social and economic benefits with more acclaimed and well-received art works.

Decoding the Amazon empire: don’t fight Bezos

Tiger Sniff Note: Matt Ward is an angel investor, start-up consultant, entrepreneur, writer and cryptographer. He published an article on thinkgrowth, detailing the development strategies of the four major science and technology giants in the world today. This article is the first in this series, and the original text isAmazon: The Company Consuming ConsumersInterested friends can click to read.

Compile | Crow Mounted Police

Today’s Amazon looks unstoppable.

The online book buying company founded by Bezos can now be said to be the most dominant and diversified enterprise in the world. At present, their goal is to become the first enterprise in the world with a market value of $1 trillion.

People in the scientific and technological circles have already reached a consensus on the greatness of Amazon, but this is not the case in the eyes of the public. There are still many misunderstandings about this company, so it is necessary for us to study it deeply.

Amazon’s empire today

Unlike most of the Fortune 500 companies, Amazon is characterized by diversification. Most companies only rely on one or two explosive products, butAmazon owns an entire army.. Supporting this "military empire" are "five pillars": Amazon website, Amazon AWS cloud service, Alexa smart speaker, Whole Foods Supermarket and Amazon Prime service.

 

One of these five businesses is enough to amaze the world; So once they are combined, the final "completed body" must be the largest commercial ship in the world.

In order to better understand this behemoth, you need to know about this "five pillars" first.

1. Amazon Mall: the world’s number one e-commerce supermarket

In the eyes of westerners, Amazon is the most monopolistic enterprise in the world, and its position can almost be said to be unshakable. Take a simple data: last year, their revenue was $136 billion, with a double-digit growth rate.

What is even more frightening is that this company is expanding their market territory almost every year. At present, Amazon has won the top 10 major markets in the world. In addition to the earliest North America and Europe, Japanese, China and Indian in Asia also have their footprints. At present, they are establishing a new "base area" in Australia.

More importantly, the train of e-commerce is still roaring forward. Thanks to the strong logistics system construction and the blessing of third-party sellers on the platform, Amazon has actually become a full-category online mall. According to 2017 data, Amazon accounts for 44% of the US e-commerce; And they have increased by at least 13% every year for the past five years.

This growth is not limited to the United States. In Amazon’s total revenue in 2016, 35.5% was contributed by overseas markets; In 2015, this figure was 34%. In the end, the double harvest in domestic and international markets contributed to the soaring of Amazon’s stock.

But there is one project that needs to be pointed out in particular, and that is Amazon Besi.(Amazon Basics). For sellers who have done business on this platform, Amazon Basics is definitely an ugly word. The platform was originally a gathering place for Amazon’s third-party sellers, but Amazon officials secretly collected the sales data of these sellers, found the most popular products, and then launched "counterfeit products" on their own main platform.

I have seen dozens of products "fortunately" copied by Amazon; I have also witnessed many friends being suppressed by Amazon in this way. exactly,Besides consumers, the only thing Amazon cares about is its main platform.This dirty trick against third-party sellers also indicates Amazon’s future business thinking: now, all third-party sellers on Amazon Besi have been replaced by Amazon’s own business-yes, Amazon only wants to monopolize consumers, and they don’t even want to leave any profits to others.

This kind of thinking is not only aimed at sellers, but also at buyers. For sellers, of course, entering Amazon will get considerable benefits, but Amazon is like junk food. Occasionally, it may taste great, but long-term consumption will bury health risks for itself. Brands are scrambling to squeeze into Amazon, which is nothing more than taking a fancy to hundreds of millions of consumers on the platform; But what they don’t know is that this kind of attempt is actually to quench thirst by drinking poison. Although entering Amazon can bring short-term benefits, in the long run, it is more likely to lose money.

The market is dead. Because the platform builder has become a market competitor.

Excessive support for self-operated products objectively reduces consumers’ choice space, and also makes Amazon’s bargaining power continue to rise. So for consumers, this is not a good thing.

2. AWS: the world’s first network service company

Although Amazon’s e-commerce business is already extremely powerful, in contrast, AWS’s performance is even more eye-catching.(Note: I personally think that Amazon should divest AWS business as soon as possible before the regulatory authorities start to implement anti-monopoly measures)

The purpose of Amazon to build AWS is to better serve its own market. They need AWS to empower Amazon.com with excellent image and information processing capabilities. Only in this way can Bezos be Bezos, and Amazon’s products can maintain their consistent modular style.

AWS is growing, and Amazon Mall is constantly cutting prices. Obviously, this is to crack down on competitors in the same industry, and one of the final results is to make AWS more competitive in the market.

 "Your profit is my opportunity"-Jeff Bezos

Today, 42% of websites are supported by AWS. This figure is even more than the combined market share of cloud services of Microsoft, Google and IBM.

However, considering that AWS is easy to use and reasonably priced, this result is not surprising.

Similar to the e-commerce business, the growth trend of AWS shows no signs of slowing down at all. At present, this business has accounted for 10% of Amazon’s total revenue, and the revenue in the third quarter of 2017 was 4.6 billion US dollars, a year-on-year increase of 42%; Net profit reached $1.2 billion, an increase of 12% over the same period in 2016.

The foundation of most websites is based on Amazon’s infrastructure.

3. Alexa: the world’s number one voice assistant

In 2014, Amazon’s "Monster Family" was added.

For those who have no need to buy books, Amazon is not in a hurry.,Because they will always find a way to include you in their network, so in the end you will realize that,The goal of this company is to win all customers.

And Alexa is the concrete embodiment of this ambition. With the sudden explosion of Alexa products, Amazon spies can finally sneak into your home.

Want to know why I say this?

Just ask a simple question: "How do you buy things?"

Alexa exists to replace all products, and its goal is to make you buy everything smoothly and seamlessly. Compared with voice communication, the mode of clicking and ordering is too primitive.

 "Hey, Alexa, we’re out of toothbrushes and toilet paper … by the way, buy another cotton ball!"

For Amazon, the subtlety of Alexa lies in choice.  

In the past, most users would choose their favorite brands when shopping in Amazon official website; But now, the appearance of Alexa will change this habit. As the above example shows, when a user wants to order Alexa to buy some daily necessities, he will generally only declare to the latter that he wants to buy a certain type of product, without emphasizing the specific brand of the product. So over time, users will find that almost everything they buy comes from the same platform-Amazon Besi.(Because Alexa’s default shopping platform is this). Since Amazon Besi has become the sales platform of Amazon’s self-operated products, this consumption habit cultivated by Alexa will eventually enable Amazon to successfully defeat other well-known brands on its own platform.

I know that many users love Echo mainly because of Alexa’s wonderful voice. But I have to tell you that this is just a means for Amazon to achieve its goal, and their real goal, as I said above, is to be the only provider of your daily necessities. At present, Alexa’s work is progressing smoothly. According to the data provided by Amazon, in the third quarter of last year alone, they sold more than 20 million Echo sets. I can’t imagine how much this number will increase on holidays …

Further, what if Amazon decides to provide you with food?

4. Whole Foods Supermarket: the 10th grocery store in the world.

Oh, wait, Amazon bought Whole Foods Supermarket for about $13 billion in 2017. So now, things become more interesting …

In a word, Amazon has bought a complete sales network with complete functions and balanced supply and demand.

Amazon’s ambition to covet the food retail industry has long existed, but because of transportation problems and food preservation problems, Amazon’s previous efforts ended in failure. The acquisition of Total Foods is a new opportunity for Amazon. Thanks to the complete supply chain of Whole Foods, Amazon can greatly reduce the supply risk and provide various food products for online customers. Of course, there will be some bad situations, for example, some ham and cheese can not be sold online; But this is just as well. Amazon will choose to significantly reduce the prices of these products in physical stores to clean up the inventory.

The addition of the whole food will also make more new scenes in the interaction between users and Alexa, such as:

 "Hey, Alexa, I want a gallon of milk, a loaf of bread, two barrels of yogurt and a jar of peanut butter. In addition, my recipe also includes pizza crust, ketchup and pepperoni. Please add these to my shopping cart! "

Similar scenes can lead to more possibilities. A realistic and reasonable imagination is that Amazon uses AI to recommend many dishes for you according to your favorites, and you are responsible for checking the dishes tonight, while Amazon will automatically place an order for you. Buy ingredients. What do you think? Is it interesting?

Now you can see why the market value of major supermarket chains evaporated by $13 billion after the acquisition was completed …

5. Amazon Prime: the second video service platform in the world; The sixth music streaming media service platform in the world

 The last of Amazon’s five pillars business is a bit complicated. On the one hand, Amazon Prime provides free 2-day delivery service in the United States, on the other hand, it is a streaming media entertainment content platform.

This is an excellent "flywheel connector". Research shows that the average spending of Prime customers is twice that of non-members.($1,300 vs $700)But if Amazon decides to reduce the membership fee to $7.99/month, they may earn more.

The reason lies in Prime Music and Prime Video. Both of these services provide unlimited free streaming services, which enable all authorized and original content of Amazon to compete directly with services such as Spotify and Netflix.

Although there is less original content on the Prime platform at present, and the quantity is less than those of Amazon’s competitors, the key point is-free. As we all know, free services can firmly bind users to Amazon’s product ecosystem.

If you can get 2-day free mail service without using Netflix and Spotify, I guess you will definitely check more products.

It is estimated that there are currently 63 million families in the United States who are Prime members, accounting for about 35% of the total population. Prime service increased Amazon’s recurring revenue by $1.9 billion in the first quarter of 2017, and doubled the purchase volume of almost every household-but this is not enough. For the number of members, Amazon’s principle is only four words: the more the better.

Amazon has "five pillars of business", any of which is enough to stand tall.

But the story is not over yet, and Amazon still has broad future development opportunities.

Amazon’s growth opportunities

Looking ahead, Amazon’s strong leadership and foresight are enough to make them invincible in the competition. The five main businesses all have great development potential and will usher in strong growth in the future.

However, Amazon is not satisfied with this. They are investing heavily in the next potential opportunity. Let’s take a look at them one by one:

1. Expand the market territory of Amazon Besi.

As mentioned above, Amazon Besi is the ultimate answer of Amazon Empire. Control the end-to-end service and you win everything. At present, although Amazon has invested a lot of resources in this business, they still have a long way to go.

As of December 14, 2017, Amazon Besi had 1,500 products.(300 models in 2013)However, with reference to the 480 million products of Amazon official website, the improvement space of Amazon Basics is full of imagination.

2. divest AWS business

I have always believed that Amazon is on the cusp of regulation. Although unlike Facebook, Google and Twitter, it is often at the forefront of public opinion, Amazon has approached the red line of supervision in many fields, naturally because of alleged monopoly.

As people and legislators gradually deepen their understanding of the Internet industry, it is only a matter of time before relevant departments get involved in Amazon. Prior to this, Amazon should pre-empt the AWS cloud service and stay away from the attention of antitrust agencies. After all, AWS is the only one of Amazon’s five branches that does not focus on business and logistics; This business is also the most suitable for independent development among the "five pillars".

Once the business divestiture is completed, the possibility of government intervention will be greatly reduced. What’s more, we all know that no matter what Amazon does, its share price will rise. Therefore, it can be predicted that the total market value of the new company and Amazon parent company after AWS independence is likely to exceed the current figure of 604 billion US dollars.

3. Expand the offline retail industry

Amazon seems to have made up its mind to build an offline physical retail store. Although the one-click online shopping model has made them earn a lot of money, they are also very aware of the importance of offline shopping experience. Some people think that once the physical retail store is completed, Amazon.com will become an important hub for users’ offline conversion rate and sales promotion; And Amazon’s offline stores will in turn boost the turnover of Amazon official website.

I basically agree with this statement. After all, Americans really like to try on clothes in offline stores. In my previous article, I also mentioned that if you really want to build a physical store, then the goods in the store must have at least one of the following two characteristics:

4. Increase the proportion of video content

Have you seen The Big Sick? This is a movie made by Amazon Studio, and the producer is Kumail Nanjiani. For a long time, I thought it was one of the most wonderful movies I have ever seen.

In 2017, Amazon spent $4.5 billion on original content. They saw the defeat of Netflix(market value of 90.57 billion US dollars)Hope, and the weapon is the original video program on Prime Video. Yes, Amazon has realized that streaming media is the future of video entertainment content.

As Amazon constantly updates its own video library, their evergreen content will not only please old customers, but also continuously contribute new members to Amazon Prime.

In a content(attention)For the king’s world, Amazon has successfully owned users’ hearts, brains and wallets.


5. Pay attention to the food industry

After winning Whole Foods Supermarket for $13 billion, the market value of American grocery industry reached $800 billion, which is six times that of Amazon’s global sales.

This contrast is obviously meaningful. However, if Amazon wants to succeed in this vast market, it must concentrate on properly allocating resources. I believe that if the decision is correct, Amazon has the opportunity to quadruple its sales in the next few years.

6. March into the pharmaceutical industry

The pharmaceutical industry is a big business in the United States, and Amazon certainly knows it. It is reported that Amazon’s actions in the pharmaceutical industry have aroused the concerns of major pharmaceutical companies such as CVS and Walgreens.

It is estimated that by 2021, the US prescription drug market will reach $610 billion. This market is close to the food retail industry. Considering that Amazon has the best logistics system in the world, if they choose to enter the pharmaceutical industry, it will be as easy as taking a walk in a nearby park.

Once there are generic drugs of Amazon brand, how many consumers will go to those inconvenient and expensive pharmacies?

It’s time to push some pills.

Other elements to consider.

I wrote in my previous article about how technology giants beat start-ups in the way they are best at; As I mentioned before, Amazon is definitely an expert in this respect: few companies are as ready to deal with all kinds of subversive changes as they are.

leadership

Amazon is one of the best managed companies in the world.

There are many reasons for this conclusion. Amazon follows a result-oriented corporate culture and encourages employees to take risks. The company pays attention to consumers, welcomes constructive criticism, and its employees have a sense of ownership.

Of course, you may think that the above words are exaggerated, but if you have a chance to observe them carefully, you will find that Amazon is really practicing the rules they have made.

Besides, Jeff Bezos did some other things. One of the most important things is the emphasis on commitment. Bezos requires employees to be firm and have strong mobility.

As you can see, whether it is the acquisition of Whole Foods or the announcement of its entry into the pharmaceutical industry, Amazon can gain immediate market recognition in almost every action. In the eyes of the public, Bezos has never missed it.

The ruthless, safe and reliable image carefully created by Bezos allows Amazon to transcend the temptation of short-term profits and always leave enough room for future development.

Of course, this also allows Bezos himself to hold a 17% stake in the company and become a veritable helm of this huge ship.

automation

Have you seen Amazon’s warehouse? If not, I suggest you watch the relevant videos.

The operational efficiency and automation level of Amazon warehouse are unmatched by others. Here, everything will be accurately measured, which enables them to try their best to reduce costs while still ensuring the high quality of products. In the case of large-scale production, this means higher unit economic benefits.

artificial intelligence

I just want to say: Amazon has the best AI experts in the world.

Whether it’s those guys who study Alexa, engineers who do millions of A/B experiments every day, or experts who focus on product recommendation system … Let’s just say that in terms of data processing ability and machine learning, the only one that can compete with Amazon is Google.

strategic acquisitions

Although Amazon has become the world’s top technology company.(if not the best in the world)However, their bank accounts are slightly smaller than those of other competitors in the industry: $22 billion in deposits prevents Amazon from making aggressive acquisitions.

However, after the acquisition of Total Foods last year, Amazon’s stock soared by 32%. This fully demonstrates the market’s trust in Bezos. Based on this reality, if Amazon decides to invest this $22 billion for a strategic acquisitions in the future, the market is likely to give positive feedback again.

Here are six areas where Amazon may make strategic investments:

1. Video industry

As a result, Amazon has invested more and more in Prime Video, and the competition with Netflix has become more and more fierce. The acquisition of a video production company is in line with business logic for Amazon, and there are many potential candidates who meet the standards.

At present, Amazon seems to be unable to afford Netflix. However, if this acquisition really happens, the consequence will be to completely kill cable TV and make Amazon an entertainment content industry.(and other related industries)The czar.

With Disney taking Hulu and time warner Inc. taking HBO, these two acquisitions are hopeless. If Amazon can win one of them before them, it will definitely be a huge victory.

Amazon’s most realistic goals at present should be the smaller film studios and the original video producers on YouTube. As we all know, YouTube is full of various and different styles of video content. If Amazon can attract all those video producers with different styles, then Prime Video can meet the needs of most users in terms of content.(You may even drag users on YouTube.)At the same time, the organic combination of long and short content will also hit Netflix and YouTube indiscriminately.

2. Music industry

Like video, Prime Music is also an important driving force for the expansion of Prime subscription service. Therefore, there is no doubt that investing in music is in line with the development plan of Amazon executives.

But unlike video, the price of buying a music company is lower, but the profit may be more considerable.

As the most commonly used music streaming service platform in the United States(I mean the free version)Pandora’s market value is only $1.33 billion. If it is acquired, Amazon will usher in a big change. The giant can make a big fuss between distribution and licensing agreement, and either one will give them more subscribers.

Another potential acquisition target is SoundCloud, a streaming music platform that is rumored to be bankrupt almost every few months. However, although they haven’t found a clear business realization idea, joining Amazon will be a win-win result for both parties.

Because SoundCloud is an interesting plug-and-play component, it fits well with Amazon’s existing platform foundation and user habits.

Up to now, SoundCloud has received $467 million in financing. However, it is not worth the price now. This affordable acquisition can reward investors and boost Amazon’s greater success.

Not only that, SoundCloud can also provide Amazon with the opportunity to enter the podcasting industry.(Another field with great potential).

3. Giant entity Shangchao

In stark contrast to the booming e-commerce industry, the traditional retail industry is increasingly depressed. However, if Amazon decides to enter the physical retail industry, then direct acquisition is obviously more cost-effective than self-built stores. The cooperation with Target will be a mutually beneficial cooperation, which is equivalent to a fatal blow to the common rival of the two companies-Wal-Mart.

Target has 1,828 branches in North America, although in Amazon’s view, these stores may be too big.(resulting in high maintenance cost)But this is not a big problem. Target’s distribution ability, storage space and sales ability are the key to attracting Amazon. Especially, considering the market value of Target is only $37.58 billion.(Only about 1/9 of Wal-Mart’s)Amazon can afford such an acquisition.

Add another fact: Target’s old customers are also Amazon’s ideal customers..

4. Fashion industry enterprises

Amazon is expanding into the fashion industry. Different from many other products, clothes in the fashion industry are not only fit, but also glamorous.

It is precisely because of this that the significance of clothing stores lies not in function, but in feeling; The driving force of sales is not the clothes themselves, but the try-on experience. Putting on beautiful tops and tight jeans is the fundamental reason why people are willing to pay.

So, if Amazon decides not to buy a full-category retailer,(such as Target)Instead of focusing on the fashion industry itself, Nordstrom is a good choice. This luxury clothing store has 349 branches in North America, and its market value is only $8 billion, which is similar to that of Whole Foods.

In addition to Nordstrom, Kohl, Macy, J.C., and Penney can also be included in the shortlist.

Don’t forget Amazon Besi, their goal has always been to turn all good products into their own. Through such an acquisition, Amazon designers can get closer to customers and quickly iterate on fashion trends across the country.

Realistically speaking, Amazon’s fashion ambition is still difficult to see, but we might as well give them two years to see if this online shopping giant can also win a place in the fashion world..

5. "Wild Ace" shared travel

This seemingly wild idea is not wild at all. Considering the huge potential of the taxi industry and Uber, it is definitely an ideal choice to win Lyft now. Let me explain to you why:

At present, the unit economic benefit of carpooling business is not good. Because of the dual characteristics of localization and globalization at the same time, the war between taxi companies can occur in every city in the world, and in the end, it is difficult for both sides to make a profit.

But what about brand advertising? How much value will it bring to your brand if the advertisement in the taxi can attract passengers’ attention?

From this perspective, Lyft is likely to become Amazon’s "sales engine".

In South Africa, Uber drivers often put a screen in the car that can play advertisements, so as to bring higher customers to Uber. Amazon can also learn from this promotion form, whether by signing a cooperation agreement or direct acquisition, Amazon can make a fortune. By understanding the positioning information of passengers, Amazon can promote their Prime Music and Video services in the local area, and also promote the sales of the online shopping platform itself. In other words, Lyft can become Amazon’s "high value-added old driver".

In addition, Amazon can also increase the bet on the Prime service, so that members can get more discounts when using Lyft to take a taxi. This will not only further tap the potential of Lyft, but also increase the number of Prime users.

Even if you think that "car ownership is dead" and "driverless is the future", it will not affect Amazon’s income in this field. To be exact, the popularity of self-driving cars will give Amazon more space to plan and arrange passengers’ "car life".

6. The telecommunications giant of Wild Ace

Imagine what would happen if Amazon won the Sprint? I know it is the smallest compared with other telecom giants, but Rao, Sprint also has 50.4 million customers.

Another important message is that Amazon itself is a platform for many users to buy mobile phones. Think about it, if Amazon says that you can get a month’s free phone service on Sprint by buying a mobile phone on the platform.(or other attractive conditions)Guess how many people will be willing to "take the bait"?

Because you have free advertisements on your own platform.(I mean Whole Foods). Amazon can easily carry out mobile sales services.(After all, most retail stores have started to handle prepaid package business now.).

Sprint is currently valued at 22.76 billion, which Amazon can still afford. This acquisition will have a significant impact on the existing competitive landscape of the telecommunications industry. Considering Amazon’s consistent style-lowering prices and reducing profits-users are likely to flock to Sprint, which will certainly increase the added value of this acquisition and effectively attack competitors.

grade

In fact, it is difficult for me to give Amazon any score except A+, but considering some unstable factors of the company itself and the potential impact of decentralized blockchain start-ups,I think the grade A is more reasonable.

In fact, Amazon has only two weaknesses: one is the potential regulatory risk, and the other is the high operating cost. Although I haven’t mentioned the latter in this article, it is still a topic worth discussing.

As of now, Amazon still does not have it.(although it is close)Profit. And that’s why Bezos can’t get an A+ from me. Although the market is still saying that "it doesn’t matter whether it is profitable or not", we all know that the climate may change at any time. Once the capital market changes dramatically and Amazon is affected, their stocks are likely to be turbulent.

But even so, I am still optimistic about Amazon. Welcome the future monopolist, he is Mr. Jeff Bezos.

tag

Amazon is really a great enterprise.

This "five-headed dragon" occupies a dominant position in almost all his fields. Never go against Bezos, you won’t get good results.

Comment | A large amount of data in new drug trials is suspected of fraud? Don’t trifle with drug safety.

  CCTV News:In the process of medical clinical experiments, in order to observe the safety and metabolic process of drugs, it is necessary to test drugs on healthy people, and professional drug testers came into being. Recently, a survey on "Drug Testers Pass the Physical Examination by Controlled Intermediary" said that every link of subjects, intermediaries and pharmaceutical companies "may be counterfeiters".

△ On October 31st, an intermediary was recruited in a 3A hospital in Beijing to check the subjects’ ID cards. (Photo/Beijing News)

  "Drug Testers Pass Physical Examination by Controlled Intermediary"(Excerpt from the report)

  Drug testers muddle through the physical examination

  It is not uncommon for the subjects to cheat in clinical trials of drugs, especially to get away with it in physical examination.

  Various methods of muddle through are popular among the subjects: smokers want to pass the urine test, and they can drop one or two drops of white vinegar during the urine test; Use 10 times the dosage of bifendate to deal with the drinking problem, so that transaminase will become normal; For another example, you can get away with it in another hospital by applying some liquid foundation to the needle holes of your arms. Some subjects swallowed the medicine in front of the doctor and then spit it out after leaving the doctor’s sight.

  The clinical examination of drug testing goes through the motions

  Screening subjects require a 5-day interval, that is, they cannot participate in the next hospital screening … … On December 7th, the reporter went to Beijing No.1, No.3 and No.3 Hospital for a medical examination. Because he registered for a medical examination in another hospital on the 6th, it was still in the interval when checking his ID card. After a simple inquiry, the nurse indicated that the interval could be changed. After simple operation, the reporter’s ID card passed the hospital system and he can continue the medical examination.

△ On November 3rd, in a major hospital in Beijing, the doctor screened the eye of the needle for the subjects during the physical examination of drug testing. (Photo/Beijing News)

  In addition, in order to let a subject whose body mass index exceeded the standard pass the screening, the hospital nurse took her to measure her weight on several high-weight machines several times, until the data on the machines met the standard, and then printed the results.

  The efficacy and safety of drugs mainly depend on clinical trial data. However, it is doubtful whether the clinical data provided by drug testers in the report can be true and effective and become qualified clinical trial data of new drugs.

  Nearly 70% of clinical trial data of new drugs are untrue and incomplete.

  At present, the hospital or relevant departments have not expressed their views on this survey from the media. However, since last year, china food and drug administration has checked the clinical trial data of some drugs that have been declared to be produced or imported for trial, and also found some problems.

  According to the data of official website of the State Food and Drug Administration, as of March 1, 2016, due to the untrue and incomplete clinical trial data, the number of drug registration applications rejected by the State Food and Drug Administration and withdrawn by pharmaceutical companies for self-examination was as high as 1,184, accounting for 73% of the total number required for self-examination. If 165 clinical exemptions are deducted, the proportion is as high as 80%. According to a survey conducted by China Journal of Clinical Pharmacology in 2013 on domestic experimental institutions, the rate of irregular experimental records was 85. 7%.

  Cctv review

  New drug trial data fraud, must be zero tolerance!

  It has been some time since the falsification of drug clinical trial data was exposed. This is by no means a "cold" that can heal itself, but a serious illness that must be treated as soon as possible.

  Do not forget your initiative mind, an effective producer supervisor to ensure drug safety.

  It is the common expectation of all patients to get rid of the disease, and a true, standardized and complete clinical trial is the source guarantee of drug safety and effectiveness. Once the clinical fraud, the drug is "three-point poison" without listing. Historically, there have been many new drugs that have been put into production quickly without strict clinical trials, such as the use of penicillin. But that was forced by the situation. It was another kind of conscience to actively put into production in World War II just to seize life against time. Today, there is no such space-time environment. Today’s drug conscience is the most scientific and serious attitude. As Bi Jingquan, director of the State Food and Drug Administration, wrote, "Neither producers nor regulators can forget the initial intention of ensuring the safety and effectiveness of drugs." 

  The chain of links is out of control, making fake data an opportunity.

  In the article, Bi Jingquan also mentioned that "for the problem of data fraud, we must use ‘ Zero tolerance ’ Attitude. " New drug trials can be done by one party alone, and it is often not the responsibility of one party to get away with data fraud. The reason is often because of the chain out of control from pharmaceutical companies to clinical trial contract organizations (CRO), from researchers in clinical trial institutions to regulatory authorities. On the road of new drug testing, pharmaceutical companies are desperately in a hurry, the experimenter helps to open the "green light", and the regulator does not issue a ticket in time, which leads to such a result. 

 

△ data map

  Prolonging life and saving life need to ask drugs for curative effect, and curative effect is the "life" of drugs. Once the hidden rules of fabricating data, tampering with data and concealing data become popular, the medical ethics that takes life seriously will have nowhere to go. The script should not be taken like this. If the pharmaceutical company as the applicant can strictly fulfill its supervisory responsibilities in accordance with the Good Practice for Clinical Trial Quality (GCP); If the clinical trial contract organization (CRO) entrusted by the applicant is not blinded by interests; If clinical trial researchers can not forget the awe of doctors, if clinical trial institutions check the research results, and if some drug regulatory authorities do not become a mere formality in on-site inspection of clinical trials … … If these were established one after another, there would be no such problem. 

  Four "most" should be implemented in safety supervision

  There have been too many lessons in the field of food and medicine. The lesson of melamine has just passed, and the Shandong vaccine case has hit the confidence of the whole society by half. Undeniably, in the field of drug research and development, China is still a latecomer in the catch-up stage, but this does not constitute the reason of "wanting money but not dying" and "picking up sesame seeds and losing watermelon". Therefore, Wang Yang, Vice Premier of the State Council, put forward four "most important" points when he visited the State Food and Drug Administration this year: to implement the most stringent standards, the most stringent supervision, the most severe punishment and the most serious accountability.

  As far as drug clinical trials are concerned, the premise of strict responsibility is to clarify responsibility. Theoretically, the applicant for drug listing bears full legal responsibility for the registration data, while the project researcher and clinical trial contract organization (CRO) of drug clinical trial institutions bear direct responsibility for the authenticity and integrity of the data, while the drug clinical trial institutions are indirectly responsible.

  However, in practice, the supervision of clinical trial institutions and contract research organizations (CRO) is still loose, and there are almost no hospital institutions and contract research organizations (CRO) that have been publicly dealt with because of data fraud in clinical trials. This state must be reversed as soon as possible.

 

△ data map

  Of course, to solve the problem, it is necessary to sort out the source. The data of new drug trials is fraudulent, on the one hand, it is negligent in supervision, on the other hand, it is tired of testing. Because in addition to active fraud, there is indeed a phenomenon that clinical trial institutions are "overwhelmed", which leads to irregular trials. Therefore, it is necessary to achieve the matching between the regulatory capacity and the regulatory object, and also to achieve the matching between the drug clinical trial institutions and the market demand. To solve this problem, it is necessary not only to simplify the examination and approval procedures of new drug clinical trials, but also to attract more medical scientists to participate in drug clinical scientific research. Let clinical research develop as a science and technology industry, and it is also a direction to prevent the falsification of drug test data.

  Wen Yi, the Mountain of Special Contributions for CCTV Comments