Cuba’s citizens are well known for free medical care, and the medical institutions in this Caribbean island country have also developed some new special medicine treatments, which have enabled many patients to find here from Wan Li, not far from all over the world. Treating intractable diseases has become another feature of Cuban medical care.

　　[Special medicine for auxiliary treatment of lung cancer]

　　CIMAvax-EGF, an adjuvant drug for lung cancer, is a unique drug developed by Cuban Center for Molecular Immunology and registered in 2008. It can strengthen the human immune system and give chemotherapy time to respond, thus improving the treatment effect of lung cancer.

　　Eduardo Osito, deputy director of the Cuban Center for Molecular Immunology, said that the research and development of CIMAvax-EGF exhausted the efforts of the first generation of scientists in the center. It is mainly composed of epidermal growth factor (EGF) and another protein P64K. Cuban medical personnel realize that EGF molecules play a very important role in the process of tumor evolution. "CIMAvax-EGF does not directly kill cells, but it can make them hungry by preventing EGF from attaching to the cell’s self-sensor," Osito said. "This correlation is the key to prevent cell growth and proliferation."

　　Unlike many other cancer therapies that have serious side effects, patients who use CIMAvax-EGF have a good tolerance to drugs. According to Osito, 30% of patients treated with this drug have significantly improved their quality of life.

　　In view of the current treatment situation of the drug, scientists believe that it is likely to have potential curative effect on cancer cells such as head and neck cancer and colon cancer that depend on EGF growth.

　　Cuba’s national medical system used this special medicine for the first time in 2012, and thousands of patients have benefited so far. At present, four countries use this medicine.

　　In January this year, Roseveare Park Cancer Institute cooperated with Cuba, and the drug began clinical trials in the United States, and it is planned to be approved by the US Food and Drug Administration (FDA) for use in the American market.

　　[Gold Award-winning Diabetes Drugs]

　　Heberprot-P is a new special medicine introduced by Cuba in 2006 for treating diabetic foot ulcers. Its appearance has saved a large number of patients from amputation.

　　The medicine is a unique product developed by Jorge Bellanga, a Cuban scientist, and the team of the Center for Genetic Engineering and Biotechnology. It contains the active pharmaceutical ingredient of epidermal growth factor (EGF) and works by direct infiltration or injection into the injured area.

　　Dr. Manuel Raisez, a member of the research team of the Center, said: "With each injection, amino acids and protein compounds can differentiate cells, and healthy and energetic tissues begin to be injected into the ulcer site. After an average of about three months, the wound is completely healed."

　　In 2007, Cuba built a clinic specializing in treating diabetic foot ulcers, but the demand far exceeded expectations. The Cuban Ministry of Health decided to start a national treatment project, and there are 458 specialized clinics at present.

　　Laissez said: "This makes our current diabetes amputation rate in the world the lowest, only 3.8%." He said that there are nearly 1 million diabetic patients in Cuba, and there are about 35,000 cases of diabetic foot ulcers every year. In 2016, only 480 cases were actually amputated.

　　Laissez and scientists from the Center have given lectures on the drug and its use in more than 20 countries, including Russia, Kuwait, Algeria, Argentina, Ecuador and Venezuela. At present, Heberprot-P has been registered in 23 countries and has been effectively used in 10 countries.

　　The implementation of this project in Cuba has been internationally recognized. It was launched to the international market 10 years ago and won the gold medal of intellectual property rights awarded by the World Health Organization.

　　[biopharmaceuticals become Cuban characteristics]

　　The research and development of new special drugs reflects the achievements of Cuba in developing medical biotechnology industry for many years. Dengue fever in the early 1980s prompted Cuba to develop Interferon；, which can stop potential viruses. In 1990, the hepatitis B recombination vaccines was developed, which almost eliminated hepatitis B in Cuba. A single dose vaccine called Heberpenta can protect against diphtheria, tetanus, whooping cough, hepatitis B and influenza B.

　　Other famous drugs developed in Cuba include Pentavalente for treating virus infection, Estreptokinasa for treating heart disease, PPG for treating cholesterol disease, Nimotuzumab for treating head and neck cancer, Eritropoyetina Human Recombinants for chronic anemia and granulocyte colony stimulating factor (g-csf) in leukemia patients.

　　Cuba has also developed many botanical drugs. The Natural Medicine Center under the National Scientific Research Center of Cuba uses palm tree fruit extract to make drugs for treating benign prostatic hypertrophy; Extracted from local wild plants in Cuba and made into drugs for autoimmune diseases; Abexol；, an antioxidant drug with anti-aging effect made from purified beeswax extract; Calcium supplement Suplecal；; Prevenox； for treating osteoporosis; PPG for controlling cholesterol level made from sugarcane extract, etc.

　　[Special medicine breeds medical tourism]

　　In the 1990s, in order to reverse the huge impact on Cuba’s economy after the disintegration of the Soviet Union, the Cuban government made great efforts to develop the tourism industry in order to obtain the foreign exchange badly needed by the country. With Cuba’s opening up to foreign tourists, tourists found that Cuba had a high success rate in treating many diseases, some of which were even better than their own countries, and medical tourism came into being.

　　Established in 1987, Cuban Medical Service Agency (SMC) mainly provides medical services for foreigners. Dr. Ianna Alvarez, director of the agency’s sales department, told reporters that SMC has signed agreements or established strategic partnerships with about 41 countries, that is to say, SMC has cooperative relations with some institutions, medical insurance companies, service export units or clinics that transport patients to Cuba for treatment.

　　Patients who come to Cuba for treatment through SMC come from all over the world, including Canada, Europe, the United States, Central America and South America. The needs of patients in Cuba are different. Many Canadian patients come to Cuba for cosmetic or plastic surgery, such as lumbar replacement, hip replacement, knee prosthesis and other treatments. Such operations need to wait for a long time in many countries; Central and South American patients come to receive nervous system treatment; Europeans mainly come to perform various eye operations and treat psoriasis, lung cancer or foot ulcers with drugs developed by Cuba …

　　Because patients come to Cuba for treatment through different channels, SMC does not have complete data, but one thing is certain, that is, the demand of international patients is increasing every year, so Cuban health authorities begin to open new foreign-related institutions and facilities in large hospitals.

　　According to Alvarez, China and Cuba have established cooperation in medical services. She said: "Because China and Cuba are far apart, it is difficult to launch a comprehensive plan for Chinese to be treated in Cuba. However, once patients have accurate information about treatment, I believe they will have high satisfaction. "

　　Alvarez said that Cuban medical services will send professionals to China to promote health care projects in the future, so that more Chinese can understand and benefit from Cuban medical services. (Ma Guihua) (special feature of Xinhua News Agency)

　　After the Hong Kong stock market closed at 16: 30 on February 19, Meituan announced that it would pay social security for full-time and stable part-time riders nationwide, which is expected to be implemented in the second quarter of 2025.

　　Following the launch of the anti-fatigue mechanism and the cancellation of overtime deduction, this is another measure taken by Meituan to improve the social security of new employment groups in recent years. According to public information, since July 2022, Meituan has taken the lead in paying new occupational injury insurance premiums for new employment groups. At present, it has invested 1.4 billion yuan to pay occupational injury insurance premiums for riders in seven pilot provinces and cities, and will further cover all riders in all provinces and cities in the future.

　　If this round of social security payment is gradually implemented, it may eventually benefit more than one million riders. According to public reports, in 2023, there were about 820,000 "stable riders who received orders for more than 260 days in a year", which should include the "full-time and stable part-time riders" described in the announcement of the US Mission. Considering that the scale of the take-away market and employment groups is still expanding, it is estimated that it may eventually cover more than one million riders.

　　According to industry insiders, with the steady development of take-away and other industries, at present, a relatively clear division of "professional" and "part-time" groups has been formed among new employees such as take-away riders. Many riders have become stable practitioners after accumulating relevant experience and skills. Providing all kinds of security for stable employment is not only in line with the actual interests of workers, but also conducive to the long-term development of the industry and the formation of a relatively stable and professional distribution group.

　　It is worth noting that since the beginning of the year, Meituan has continuously introduced heavy measures to strengthen the protection of new employment groups, including canceling overtime deductions and online anti-fatigue mechanisms, and has built 16,000 rider communities in conjunction with all sectors of society to help riders smooth the distribution path.

　　At the end of the announcement, the US Mission stated that "it will continue to increase resources and capital investment, continuously improve the rider welfare treatment system, and strive to contribute more positive forces to building harmonious labor relations."

Fuzhou Strait International Convention and Exhibition Center, the main venue of the 2nd Digital China Construction Summit.

　　Cctv news(Reporter Zhang Xiaolin, Wang Xiaoying and Li Wenliang) From May 6 to 8, the second Digital China Construction Summit will be held in Fuzhou, Fujian Province.

　　Digital China Construction Summit is a platform for publishing China’s informatization development policies, displaying the achievements of e-government and digital economy development, exchanging theoretical experience and practice of digital China construction, and gathering global forces to promote the construction of digital China. The theme of this summit is "Cultivating new kinetic energy with informatization, promoting new development with new kinetic energy, and creating new glory with new development".

　　Compared with the first summit in 2018, the new positioning has injected international elements into this summit and added a lot of highlights to this summit.

　　Aspect 1: Big coffee drives insight into the new trend of industry development

　　This summit will hold the opening ceremony, main forum, sub-forum, achievement exhibition, report release, innovation competition and closing ceremony.

　　At present, this summit has collected and sorted out a total of 498 digital economy docking projects with a total investment of 407.5 billion yuan. Ma Huateng, Chairman of Tencent’s Board of Directors, and Li Yanhong, Chairman of Baidu, have confirmed their attendance at the summit. At the same time, more than 40 academicians of the two academies, as well as guests from leading enterprises of digital economy such as Huawei, Baidu, Ali, Tencent, Inspur and Iflytek, will attend the conference, and will give wonderful speeches in the main forum and related sub-forums. The number of guests attending the conference is expected to increase by 50% compared with the first summit.

　　Aspect 2: The collision of views in 16 sub-forums is more exciting

　　Compared with the first session, not only the number of guests has increased, but also the number of sub-forums this year has doubled from 8 to 16.

　　In addition to e-government, big data, smart society, digital economy, digital Fujian, digital Haisi, Internet of Things, the sub-forum has also added digital ecology, satellite applications, industrial Internet, network technology, digital health and other contents, with more detailed themes, greatly increased focus and more intense point of view collision.

　　It is noteworthy that the organizing committee of this summit will invite some international organizations, multinational companies, foreign-funded enterprises in China and think tank representatives to participate, and will also invite government officials from countries along the Belt and Road to participate in the summit activities, share their views and exchange mutual learning.

　　Aspect 3: Pay attention to the policy release and grab the "red envelope" of the ministries.

　　Policy release will continue during this year’s summit. The Central Network Information Office, the Ministry of Agriculture and Rural Affairs, the National Health Commission, the National Space Administration and other ministries and commissions will focus on releasing policies on industry informatization and digital economy development in their respective fields, and launch a number of policy "red envelopes".

　　In the main forum, the responsible comrades of the National Internet Information Office will release the Report on the Construction and Development of Digital China (2018). At the closing ceremony, relevant national ministries and commissions will also release relevant policies and reports.

　　Aspect 4: See the exhibition and experience the new technology.

　　As a platform for releasing China’s information development policies and displaying the achievements of e-government and digital economy, what new technologies will be exhibited at the Digital China Construction Achievements Exhibition? Everyone is curious.

　　It is reported that this summit has added a sub-forum on industrial applications, and the exhibition area has increased from 40,000 square meters to about 60,000 square meters. The exhibitors basically cover all provinces, municipalities and relevant state ministries and commissions, as well as many top 100 Internet companies and top 100 electronic information companies. The development achievements of digital China and digital economy in recent years will be fully displayed, and the first exhibition rate of new technologies and new products will exceed half.

　　There are five major venues in this exhibition, and the themes are comprehensive+digital Fujian, guest province+digital government, digital economy (digital industrialization), digital economy (digital industry)+achievement release and smart society+digital life+achievement release.

　　The organizer will also launch a number of smart application scenarios in the venue, such as full-scene face payment, smart restaurants, credit blocks, driverless cars, and unmanned vehicles, and realize the full coverage of the 5G signal main venue, bringing a batch of 5G and intelligent new experiences to the guests. In addition, an "online summit" was launched to create a "year-round exhibition and never ending" summit.

　　Aspect 5: Take the entrepreneurial platform to see who is competing with the front.

　　The finals of the Digital China Innovation Competition will be held during the summit.

　　According to the organizer, the 2019 Digital China Innovation Competition aims at outstanding data scientists at home and abroad, and sets three kinds of algorithm problems: big data, artificial intelligence and industrial internet, so as to explore innovative technology applications and business models, stimulate the innovation vitality of professionals, and build a new platform for Industry-University-Research cooperation in high-tech industries.　

　　The 2019 Digital China Innovation Competition Finals will publicly defend and review the outstanding works of 18 teams that have advanced in the regional finals, and select excellent teams of data scientists and solutions to promote the in-depth integration of the new generation of information technology and traditional industries, help solve the pain points and difficulties in the development of digital economy, and help the construction of digital China.

Finding Nemo 2 and Grand Theft Auto 1

1905 movie network news In 2016, the North American film market experienced a wonderful year, with the total box office revenue reaching $11.4 billion, a record high. The box office record of $11.1 billion in 2015 is dead.

　

It is reported that the data comes from ComScore, a well-known American internet statistics company. The attendance data has not been calculated, but the company’s analysts believe that the attendance rate in 2016 will be the same as that in 2015. Without counting inflation, the realization of the box office record in 2016 benefited from high ticket prices. At the beginning of 2016, the ticket price of North American movies once reached a new high point, but the average ticket price for the whole year has yet to be calculated.

　

This record exceeded the expectations of the industry, especially the lack of "007" and two blockbuster series last year.

　

2016 was Disney’s strongest year, with its North American box office exceeding $3 billion, accounting for more than a quarter of the annual market share, and it was also the one with the least film distribution among the six major Hollywood companies.

　

Produced by Disney and Pixar, and released by Disney, the North American box office reached 486.3 million US dollars, ranking first in the North American annual box office. If you count the box office receipts in 2016 (released in North America on December 18, 2015), six of the top ten box office charts in 2016 are Disney movies.

　

The other four Disney movies are: (408.2 million dollars, up to 2016.12.31), (408.1 million dollars), (364 million dollars) and (341 million dollars).

　　Xinhua News Agency, Zhengzhou, April 12th Title: Hao Yingge, a post-95 college student: Returning the ticket, she chose to face the virus directly.

　　Xinhua News Agency reporter Zhai Zhuo

　　During the Spring Festival this year, Hao Yingge, a post-95 college student in Henan Province, probably made the most difficult and firm decision in her life — — Refund the ticket

　　Hao Yingge is a senior majoring in medical laboratory in Sanquan College of Xinxiang Medical College. In June last year, she was sent by the school to Wuhan Huada Medical Inspection Institute Co., Ltd. for an internship. Before the Spring Festival, she packed her luggage like other foreign employees in the company and prepared to take the train back to her hometown in Henan for the New Year.

　　However, the sudden outbreak disrupted Hao Yingge’s plan. At that time, Wuhan Huada Medical Research Institute had just undertaken some nucleic acid detection work on Covid-19 samples. Hao Yingge hesitated when he saw the mobilization order for the war "epidemic" issued by the company.

　　"I am a medical student, and the nucleic acid detection work in Covid-19 coincides with my major. It is my responsibility to stay." Hao Yingge said.

　　When she carefully told her family about the decision, the other end of the phone was silent. For a long time, my father Hao Jinzhou said, "Stay if you want, but you must protect yourself. Anything happens, I’ll pick you up right away. "

　　Since January 23, Hao Yingge has been dealing with the virus for more than two months. Hao Yingge once wrote such a passage on his mobile phone, "If some time ago was the day when recruits joined the army for training and exercises, then the last two months have been really on the battlefield ‘ Fight ’ . Every battle needs a group of soldiers, and I am honored to be a member of the anti-epidemic army. "

　　Information input, nucleic acid extraction, gene amplification, result analysis … … The daily inspection work is complicated and boring, but Hao Yingge has completed every link very carefully. There has never been a mistake in the virus samples she handled. "I hope to be responsible for every sample and every patient."

　　Hao Yingge said that in recent days, her life is a "two points and one line" between the laboratory and the dormitory. "At the busiest time, the laboratory tested an average of 8,000 samples per day, and 12,000 samples were tested on March 1." The continuous night shift has exhausted Hao Yingge to the extreme, but once a sample is put into storage, she will still arrive at the post immediately.

　　Hao Yingge works in the laboratory (photo taken on March 1). Xinhua news agency

　　During the daily inspection, Hao Yingge has to face the test of "ice and fire". "Our hands are operated in a safe cabinet. After a long time, our hands will become cold. At the same time, airtight isolation protective equipment often makes her feel sultry. "

　　In order to reduce the wear and tear of protective clothing, Hao Yingge will try to reduce the number of times he goes in and out of the laboratory. Every time before entering the laboratory, she often doesn’t drink water. The longest working time is that she has been busy in the laboratory for 10 hours.

　　Together with Hao Yingge, there are three other interns from Sanquan College: Li Yan, Gui Yunfei and Sun Yujie. "Gui Yunfei and I are responsible for the inspection work, and Li Yan and Sun Yujie are responsible for handling medical waste." During this time, the four young people cooperated with each other and cheered each other every day. "If you stay, you have to rush forward. We are all great."

　　Hao Yingge made a gesture of "comparing the heart" during work (photo taken on March 2). Xinhua news agency

　　When Hu Miao, executive vice president of the School of Medical Laboratory of Sanquan College, heard the stories of Hao Yingge and others, he specially held a live online broadcast for them. "Seeing the various concerns and greetings of the students on the screen of the mobile phone, I don’t want to mention how warm I am."

　　"They are just interns or children. If they choose to leave, no one will blame them. However, with their persistence and dedication, they set an example for our teachers and students. " Hu Miao said.

　　After the "unsealing" in Wuhan, Hao Yingge was filled with emotion. "I still remember that when the traffic in Wuhan resumed, I took a bus back to my dormitory in the morning and there was a traffic jam when I turned left." Hao Yingge said that the traffic was blocked, but her mood was relaxed. "Traffic jams mean more people, more cars, the city is recovering, and life is full of fireworks. This is also the goal that my comrades and I have been working hard for more than two months. "

　　After the "unsealing" in Wuhan, Hao Yingge jumped up excitedly (photo taken on April 9). Xinhua news agency

　　Hao Yingge said frankly that she never thought that her choice would gain so much attention and praise. "People around me, like me, just want to get sick people treated, and people who are not sick can feel at ease. I know that my strength is very small, but with more efforts, I can overcome the epidemic earlier. "

　　The reporter asked her if she would be afraid to face the virus directly.

　　"I’m not afraid. I just hope to win this tough battle as soon as possible and go home as soon as possible. I miss my parents!"

　　CCTV News:The data shows that the proportion of users who use mobile phones to watch videos exceeds 70%, and watching videos and live broadcasts on the move has become the urgent need of the majority of users. In order to meet the audience’s strong demand for watching live broadcasts on mobile phones, Glory has joined hands with China Telecom and CCTV Easy Orange to give away 90GB of telecom traffic free of charge to users who buy Glory’s 5C full netcom version since August.

　　Traffic is free to send live broadcasts.

　　According to the statistics released by CNNIC, 71.9% of users use mobile phones to watch videos, and the current hot live broadcast has intensified this trend. However, in most cases, WiFi signals are only available indoors. Although the speed of 4G network is fast, the huge traffic consumption has become the most troublesome problem for users.

　　In order to enable users to watch mobile video and live broadcast anytime and anywhere, Glory teamed up with China Telecom and CCTV Easy Orange to launch a special event: giving away 90GB of free traffic from China Telecom (*90GB of telecom traffic, which is directed traffic for CCTV Integrated application, only applicable to Glory Play 5C Full Netcom Edition). Users of China Telecom who purchase Glory 5C full netcom version can upgrade their mobile phone system to the latest version (B121 version or above), and open the built-in "CCTV Comprehensive" APP in their mobile phones to receive the traffic for free. The traffic will take effect on the same day, and they will be given for 6 months in a row, and 15G of local directional traffic will be given every month (subject to the operator’s notice).

　　In the "CCTV Comprehensive" APP built in Glory Play 5C Netcom Edition, the traffic consumed by users to watch programs will be deducted from the 90GB free traffic.

　　Glory and play 5C, enjoy it for a long time.

　　Glory Play 5C Full Netcom Edition is equipped with Kirin 650 chip with 16 nm 8-core, which is the first time to introduce the 16 nm process technology of the same generation as flagship models such as iPhone6s and Huawei Mate8 into the thousand yuan machine market. Compared with the 28 nm chip mobile phone on the market, Glory Play 5C performance is improved by 65%, and the power consumption of the whole machine is reduced by 40%. At the same time, it supports 4G+ technologies such as carrier aggregation and Cat.6, and the downlink speed can reach up to 300Mbps.

　　In this way, under the extremely fast 4G network, using the Glory 5C equipped with 16 nm 8-core to watch live video, the buffer is fast, the load is fast, the video is more refreshing, the heat is less, the power consumption is less, and the video can be played for a longer time, thus getting rid of the double pain that the progress bar can’t be dragged and the traffic can’t be hurt.

　　Watch the wonderful things anytime, anywhere.

　　CCTV mobile TV service was officially launched in December, 2006. It is committed to building the first cross-media interactive mobile TV station in China and providing the most authoritative, convenient and beautiful mobile video viewing service for mobile phone users in China. Information broadcast at home and abroad, the first time to take you to the news site; The hot events in the European Cup and the Olympic Games continue; CCTV famous columns, Spring Festival Gala, two sessions, military parade and other exclusive hot columns, witness the passionate moment of major events! Now all you need is a glory to play 5C full netcom version, which is exciting anytime and anywhere, and 90GB free traffic is waiting for you!

　　Beijing Yi Orange Tianxia Technology Co., Ltd. is a wholly-owned subsidiary of CCTV, and the only authorized operator of CCTV’s mobile TV integrated broadcast control license and content service license; It is the only channel for CCTV’s massive and high-quality copyright content to be exported to mobile terminals. Approved by the State Administration of Radio, Film and Television, the call sign of CCTV mobile TV content service license is "CCTV mobile TV" and the call sign of integrated broadcast control license is "China mobile video".

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Unconsciously, the Spring Festival holiday has ended, and many people have returned or are on their way back. Are you ready to start the work mode? What should I pay attention to before and after returning? What adjustments are needed to start work, diet, work and rest after the holiday?

After the Spring Festival holiday, many people set foot on the return journey. What should they pay attention to before, during and after the trip? After the long vacation, some people may have symptoms such as sleep disorder, anxiety and depression. How to alleviate and deal with "holiday syndrome"? A picture to understand.

Is it difficult for you to eat on time? Rushing to work and class in the morning, giving up breakfast after breakfast; Working overtime until late at night, you can only fill your stomach with snacks and supper. Even in order to lose weight, eating one less meal every day is designated as a personalized "rule" for eating.

Original Tencent medical code　

Never think that "vaccination is a child’s business". Even if you are an adult, it is very important to vaccinate in time & it is very important to replenish the vaccine that was missed before.

According to the report of the Centers for Disease Control and Prevention (CDC), 50,000 to 90,000 American adults die of vaccine-preventable diseases every year, such as pneumococcal diseases, influenza and hepatitis [1], and this statistic does not count cervical cancer caused by HPV (more than 5,000 people died of cervical cancer in the United States in 2018 [2]).

In this article, we have summarized 9 vaccines that adults need to consider:

Influenza vaccine: suitable for children and adults over 6 months old.

Herpes zoster vaccine: suitable for people over 50 years old.

23-valent pneumococcal polysaccharide vaccine: recommended for people with special health conditions over 2 years old and the elderly.

HPV (human papillomavirus) vaccine: suitable for all women aged 9-45.

Hepatitis A vaccine, hepatitis B vaccine and hepatitis E vaccine: Adults should also be vaccinated in time.

Chickenpox vaccine, measles, rubella and mumps vaccine: special circumstances, protecting adults.

If you don’t want to read the text, you can directly drop it down to the end of the article. We have sorted out the suitable vaccination population and vaccination methods of these nine vaccines in detail, and summarized them into a table for you to save to your mobile phone for comparison.

Many people misunderstand the lethality of the flu and think that the flu is just like a cold.

In fact, influenza is a very dangerous respiratory infectious disease.

Influenza can cause 290,000 ~ 650,000 respiratory disease-related deaths worldwide every year [3].

Maybe you will think, "I’m an adult and I’m in good health, so I don’t have to fight."

But unfortunately, the flu is a disease that the whole population is susceptible to. Even if they are not sick, adults are running around every day, and it is easy to bring the flu virus back to the elderly or children at home.

Therefore, people of all ages over 6 months old are advised to complete influenza vaccination in autumn and winter every year, preferably before the end of October [3].

(Long press the picture to save it to the phone)

The pathogen of herpes zoster is called varicella-zoster virus (VZV), which is a neurovirus.

People who have experienced the onset of herpes zoster, the biggest feeling is "pain"-pain like knife cutting, fire and electric shock.

Many people even say that it is comparable to childbirth pain and cancer pain. In fact, the pain of herpes zoster can also lead to suicide [4].

As long as you have been infected before (such as chicken pox when you were a child), the virus may lurk in the body for a long time. Once your immunity drops, it will come out and "mess up", leading to herpes zoster.

There is no specific treatment for this disease at present, and vaccination is the most effective way to prevent it [5].

Therefore, it is recommended that people aged 50 and above should be vaccinated against herpes zoster as much as possible.

(Long press the picture to save it to the phone)

Don’t think that "pneumonia is nothing to be afraid of". In fact, in addition to "pneumonia", Streptococcus pneumoniae is an important pathogen causing meningitis, otitis media, bacteremia and other infections, and it is also the main cause of community-acquired pneumonia.

About 1 million people worldwide die of pneumococcal pneumonia every year, and the mortality rate among the elderly and high-risk groups is as high as 30%~40%[6].

Vaccination with 23-valent pneumococcal polysaccharide vaccine can effectively prevent 23 common Streptococcus pneumoniae infections that lead to invasive diseases.

The elderly aged 60 and over, as well as the special population over 2 years old, are recommended to be vaccinated with 23 valent pneumococcal polysaccharide vaccine.

(Long press the picture to save it to the phone)

Studies have shown that 99.7% of cervical cancer is related to HPV infection [7].

At present, there are three kinds of HPV vaccines on the market, 2-valent, 4-valent and 9-valent. Many people subconsciously think that the 9-valent vaccine is the best. In fact, within the allowable age, the sooner you get HPV vaccine, the better. It is best to get it before you have sexual experience.

If there is a shortage of 9-valent vaccine in your area and it is difficult to make an appointment, you don’t have to force it to be 9-valent.

(Long press the picture to save it to the phone)

It has been more than 40 years since the immunization program in China, during which it has undergone several changes: the immunization program vaccine has expanded from 4 to 14, and the preventable infectious diseases have expanded from 6 to 15.

This means that from the current standards, some adults born earlier may miss some vaccines.

You can look for your own vaccination registration book to check the relevant information, or ask your parents about their own vaccination. If you can’t remember whether you have been vaccinated, you can treat it as "not vaccinated".

If you have not been vaccinated with the following vaccines, you need to consider replanting.

Hepatitis A, B and E vaccine

China is a big country with hepatitis. Viral hepatitis with great harm mainly includes:

Hepatitis A and hepatitis E transmitted through digestive tract, and hepatitis B and hepatitis C transmitted through blood, mother and child [8].

1. Hepatitis A

Hepatitis A vaccine was only included in the immunization program in 2008, so many adults have not been vaccinated.

Although hepatitis A has been considered to be well controlled, in recent years, the incidence group of hepatitis A in China is mainly adults. Take Liaoning as an example, the local incidence is mainly adults. The vaccination target of adult hepatitis A vaccine is ≥16 years old, and children are vaccinated at the age of 12 months to 15 months.

2. Hepatitis B

Hepatitis B, which makes many people turn pale, has been effectively controlled in recent years, but it is estimated that the number of patients still exceeds 84 million, and in 2018, more than 90% of hepatitis B virus infected people are adults over 20 years old [9].

What needs to be vigilant is that hepatitis B may also transmit the virus to children through mother-to-child transmission.

3. Hepatitis E

Hepatitis E may be very strange to many people, but in fact, there are more than 28,000 cases in China, even more than hepatitis A [10].

Moreover, few people know that hepatitis E, like hepatitis A, is transmitted through the digestive tract, and even less people know that hepatitis E can be prevented by vaccines.

Therefore, if you have never been vaccinated with these three vaccines, you should complete the vaccination as soon as possible according to your own situation.

(Long press the picture to save it to the phone)

Varicella vaccine

Many people think that chickenpox is a disease that only children get. In fact, adults occasionally get sick, and the risk of complications and death of adults with chickenpox is higher than that of children [12].

Chickenpox virus is very easy to spread in a confined space, so it is recommended to vaccinate teachers, white-collar workers, pregnant women and people who may have close contact with chickenpox patients.

Anyone who has never had chickenpox, or who has only had one shot in the past, can be vaccinated or replanted.

(Long press the picture to save it to the phone)

MMR vaccine

The full name of this vaccine is "live attenuated measles, mumps and rubella vaccine", which can be abbreviated as "MMR vaccine".

The measles-mumps vaccine can stimulate the body to produce immunity to measles virus, mumps virus and rubella virus at the same time, thus preventing measles, mumps and rubella.

All three viruses can spread through droplets and are highly contagious.

Moreover, if a woman is infected with rubella during pregnancy, it may lead to congenital rubella syndrome in the fetus, resulting in irreversible consequences such as abortion and congenital malformation of the fetus [13].

In China, measles vaccine was mainly covered in the early years, and it was not until 2007 that measles vaccine was fully covered.

Therefore, most people born before 2007 suggest re-vaccination.

(Long press the picture to save it to the phone)

Finally, we have summarized the nine vaccination methods mentioned in this article for you in the following table.

(Long press the picture to save it to the phone)

references

[1]Reid KC, Grizzard TA, Poland GA. Adult immunizations: recommendations for practice. Mayo Clin Proc. 1999 Apr; 74(4):377-84. doi: 10.4065/74.4.377. PMID: 10221468.

[2]HPV Information Centre. United States of America Human Papillomavirus and Related Cancers, Fact Sheet 2018.

[3] China Center for Disease Control and Prevention, Influenza Vaccine Working Group of National Immunization Planning Technology Working Group. Technical Guide for Influenza Vaccination in China (2020-2021).

[4]Chidiac C, Bruxelle J, Daures JP, Hoang-Xuan T, Morel P, Leplège A, Hasnaoui A El, de Labareyre C. Characteristics of patients with herpes zoster on presentation to practitioners in France. Clin Infect Dis. 2001; 33:62–69.

[5] Herpes Zoster Expert Consensus Working Group of Dermatologists Branch of Chinese Medical Association. Herpes Zoster Expert Consensus in China. Chinese Journal of Dermatology 2018; 51(6): 403-8.

Chinese Preventive Medicine Association and Vaccine and Immunity Branch of Chinese Preventive Medicine Association. Expert Consensus on Immunoprophylaxis of Pneumococcal Diseases (2017 Edition) [J]. Chinese Journal of Preventive Medicine .2018,19 (3): 161-191.

[7]Arbyn M, Weiderpass E, Bruni L, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020; 8(2):e191––e203.

[8] National Health and Family Planning Commission of the People’s Republic of China. China Viral Hepatitis Prevention and Control Plan (2017-2020) [J]. China Journal of Viral Diseases, 2018.

[9]Wang H, Men P, Xiao Y, et al. Hepatitis B infection in the general population of China: a systematic review and meta-analysis. BMC Infect Dis. 2019; 19(1):811. Published 2019 Sep 18.

[10] Brief introduction of epidemic situation of Class A, B and C infectious diseases in China in December 2020 [J]. Disease Surveillance, 2021,36(01):1.

[11]Nelson NP, Weng MK, Hofmeister MG, Moore KL, Doshani M, Kamili S, Koneru A, Haber P, Hagan L, Romero JR, Schillie S, Harris AM. Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020. MMWR Recomm Rep. 2020 Jul 3; 69(5):1-38.

[12]Meyer, Pamela, A, et al. Varicella Mortality: Trends before Vaccine Licensure in the United States, 1970-1994.[J]. Journal of Infectious Diseases, 2000.

[13]Gary s. Marshall. Translated by Zhou Zumu. Vaccine Manual: A Practical Guide for Clinicians [M]. 4th Edition. Beijing: Peking University Medical Press, 2014.

Read the original text

During the Spring Festival this year, there were two war films in the film market, which triggered a movie-watching craze. The Battle at Lake Changjin’s sequel "Watergate Bridge of Changjin Lake" is based on large and medium materials, showing the "panorama" of the war; Sniper sees the big picture in a small way, which is more like a local "close-up" of the battle. The same theme of war, choosing the same schedule for release, all showed good box office appeal and word-of-mouth influence, breaking the previous market pattern of leading comedy films in the Spring Festival.

　　The theme of war has always been an important theme in film creation. In the film history of China, there have been many creative upsurge of war theme, and a number of well-known works have been born. However, for some time, domestic war films have fallen into a creative bottleneck. Some of them are full of bullets and gunfire, but they make people sleepy. There are also obvious traces of preaching, lacking the power to penetrate the hearts of the people and being "left out" by the market. From the "big" of The Battle at Lake Changjin series to the "small" of Sniper, what kind of transformation has taken place in domestic war films?

　　War movies are getting better and better, which is inseparable from the improvement of the film industry in China. The level of film industry is reflected in the typed creation, scientific and systematic production management and the application of new technologies. The creative experience of The Battle at Lake Changjin series shows that the same type of film can follow certain creative rules from script to production according to certain creative standards, and constantly replicate successful experiences to ensure sustainable production. The combination of technology and art is also an important standard of film industrialization. The Battle at Lake Changjin series created a breathtaking audio-visual experience for the audience with the help of high technology, and more than 90% of post-production and special effects technology were completed in China. At present, under the impact of online media, movies need to move towards a higher level of production, and movie audiences hope to get a completely different experience from other audio-visual platforms in the cinema. These changes urgently require filmmakers to lead the development of the industry with scientific and technological innovation. With the further improvement of film technology research and development capabilities, the unique charm of the big screen will further bloom.

　　War movies are getting better and better, which is inseparable from the improvement of China’s storytelling ability. Nowadays, war movies pay more and more attention to telling short stories in the big scene. It can not only "get both the big and the small", but also "see the small and view the big", which not only has a panoramic expression of the war process, but also vividly depicts the ordinary soldier. From this point of view, although there is no grand scene in Sniper, its characterization is deeply rooted in people’s hearts. In particular, the use of dialects, with mild comedy to describe the tragic core, so that one by one amiable and respectable image of China soldiers leap onto the screen. The cultural attribute of the film determines that it must bear the national spiritual and cultural value. Therefore, film creation should not only pursue the shock of the scene, but also the shock of the soul. When the technical means that directors can use are more and more advanced, they should also settle down and think about what kind of art form to use to recall the bonfire years and pay tribute to the "most lovely person".

　　Domestic films should not only base themselves on the domestic market, but also open their international horizons. What is worthy of recognition is that at present, while the domestic war films are promoting the main theme, the theme is no longer single, and the relationship between war and peace, war and people is deeply considered. Film art is a universal language and one of the best carriers to spread the story of China. China’s films still need to expand the breadth and depth of themes, strengthen international exchanges and cooperation, find the code of human empathy, and let the story of China really go to the world.

　　The Battle at Lake Changjin series and Sniper show us that war themes have a broad creative space. By February 9, 2022, the total box office (including pre-sale) of national cinema films exceeded 10 billion yuan, which shows the consumption potential of the film market. It is expected that China films will grow in the process of transformation, and achieve a double harvest of social and economic benefits with more acclaimed and well-received art works.

Tiger Sniff Note: Matt Ward is an angel investor, start-up consultant, entrepreneur, writer and cryptographer. He published an article on thinkgrowth, detailing the development strategies of the four major science and technology giants in the world today. This article is the first in this series, and the original text isAmazon: The Company Consuming ConsumersInterested friends can click to read.

Compile | Crow Mounted Police

Today’s Amazon looks unstoppable.

The online book buying company founded by Bezos can now be said to be the most dominant and diversified enterprise in the world. At present, their goal is to become the first enterprise in the world with a market value of $1 trillion.

People in the scientific and technological circles have already reached a consensus on the greatness of Amazon, but this is not the case in the eyes of the public. There are still many misunderstandings about this company, so it is necessary for us to study it deeply.

Amazon’s empire today

Unlike most of the Fortune 500 companies, Amazon is characterized by diversification. Most companies only rely on one or two explosive products, butAmazon owns an entire army.. Supporting this "military empire" are "five pillars": Amazon website, Amazon AWS cloud service, Alexa smart speaker, Whole Foods Supermarket and Amazon Prime service.

　

One of these five businesses is enough to amaze the world; So once they are combined, the final "completed body" must be the largest commercial ship in the world.

In order to better understand this behemoth, you need to know about this "five pillars" first.

1. Amazon Mall: the world’s number one e-commerce supermarket

In the eyes of westerners, Amazon is the most monopolistic enterprise in the world, and its position can almost be said to be unshakable. Take a simple data: last year, their revenue was $136 billion, with a double-digit growth rate.

What is even more frightening is that this company is expanding their market territory almost every year. At present, Amazon has won the top 10 major markets in the world. In addition to the earliest North America and Europe, Japanese, China and Indian in Asia also have their footprints. At present, they are establishing a new "base area" in Australia.

More importantly, the train of e-commerce is still roaring forward. Thanks to the strong logistics system construction and the blessing of third-party sellers on the platform, Amazon has actually become a full-category online mall. According to 2017 data, Amazon accounts for 44% of the US e-commerce; And they have increased by at least 13% every year for the past five years.

This growth is not limited to the United States. In Amazon’s total revenue in 2016, 35.5% was contributed by overseas markets; In 2015, this figure was 34%. In the end, the double harvest in domestic and international markets contributed to the soaring of Amazon’s stock.

But there is one project that needs to be pointed out in particular, and that is Amazon Besi.（Amazon Basics）. For sellers who have done business on this platform, Amazon Basics is definitely an ugly word. The platform was originally a gathering place for Amazon’s third-party sellers, but Amazon officials secretly collected the sales data of these sellers, found the most popular products, and then launched "counterfeit products" on their own main platform.

I have seen dozens of products "fortunately" copied by Amazon; I have also witnessed many friends being suppressed by Amazon in this way. exactly,Besides consumers, the only thing Amazon cares about is its main platform.This dirty trick against third-party sellers also indicates Amazon’s future business thinking: now, all third-party sellers on Amazon Besi have been replaced by Amazon’s own business-yes, Amazon only wants to monopolize consumers, and they don’t even want to leave any profits to others.

This kind of thinking is not only aimed at sellers, but also at buyers. For sellers, of course, entering Amazon will get considerable benefits, but Amazon is like junk food. Occasionally, it may taste great, but long-term consumption will bury health risks for itself. Brands are scrambling to squeeze into Amazon, which is nothing more than taking a fancy to hundreds of millions of consumers on the platform; But what they don’t know is that this kind of attempt is actually to quench thirst by drinking poison. Although entering Amazon can bring short-term benefits, in the long run, it is more likely to lose money.

The market is dead. Because the platform builder has become a market competitor.

Excessive support for self-operated products objectively reduces consumers’ choice space, and also makes Amazon’s bargaining power continue to rise. So for consumers, this is not a good thing.

2. AWS: the world’s first network service company

Although Amazon’s e-commerce business is already extremely powerful, in contrast, AWS’s performance is even more eye-catching.(Note: I personally think that Amazon should divest AWS business as soon as possible before the regulatory authorities start to implement anti-monopoly measures)

The purpose of Amazon to build AWS is to better serve its own market. They need AWS to empower Amazon.com with excellent image and information processing capabilities. Only in this way can Bezos be Bezos, and Amazon’s products can maintain their consistent modular style.

AWS is growing, and Amazon Mall is constantly cutting prices. Obviously, this is to crack down on competitors in the same industry, and one of the final results is to make AWS more competitive in the market.

　"Your profit is my opportunity"-Jeff Bezos

Today, 42% of websites are supported by AWS. This figure is even more than the combined market share of cloud services of Microsoft, Google and IBM.

However, considering that AWS is easy to use and reasonably priced, this result is not surprising.

Similar to the e-commerce business, the growth trend of AWS shows no signs of slowing down at all. At present, this business has accounted for 10% of Amazon’s total revenue, and the revenue in the third quarter of 2017 was 4.6 billion US dollars, a year-on-year increase of 42%; Net profit reached $1.2 billion, an increase of 12% over the same period in 2016.

The foundation of most websites is based on Amazon’s infrastructure.

3. Alexa: the world’s number one voice assistant

In 2014, Amazon’s "Monster Family" was added.

For those who have no need to buy books, Amazon is not in a hurry.,Because they will always find a way to include you in their network, so in the end you will realize that,The goal of this company is to win all customers.

And Alexa is the concrete embodiment of this ambition. With the sudden explosion of Alexa products, Amazon spies can finally sneak into your home.

Want to know why I say this?

Just ask a simple question: "How do you buy things?"

Alexa exists to replace all products, and its goal is to make you buy everything smoothly and seamlessly. Compared with voice communication, the mode of clicking and ordering is too primitive.

　"Hey, Alexa, we’re out of toothbrushes and toilet paper … by the way, buy another cotton ball!"

For Amazon, the subtlety of Alexa lies in choice.　　

In the past, most users would choose their favorite brands when shopping in Amazon official website; But now, the appearance of Alexa will change this habit. As the above example shows, when a user wants to order Alexa to buy some daily necessities, he will generally only declare to the latter that he wants to buy a certain type of product, without emphasizing the specific brand of the product. So over time, users will find that almost everything they buy comes from the same platform-Amazon Besi.(Because Alexa’s default shopping platform is this). Since Amazon Besi has become the sales platform of Amazon’s self-operated products, this consumption habit cultivated by Alexa will eventually enable Amazon to successfully defeat other well-known brands on its own platform.

I know that many users love Echo mainly because of Alexa’s wonderful voice. But I have to tell you that this is just a means for Amazon to achieve its goal, and their real goal, as I said above, is to be the only provider of your daily necessities. At present, Alexa’s work is progressing smoothly. According to the data provided by Amazon, in the third quarter of last year alone, they sold more than 20 million Echo sets. I can’t imagine how much this number will increase on holidays …

Further, what if Amazon decides to provide you with food?

4. Whole Foods Supermarket: the 10th grocery store in the world.

Oh, wait, Amazon bought Whole Foods Supermarket for about $13 billion in 2017. So now, things become more interesting …

In a word, Amazon has bought a complete sales network with complete functions and balanced supply and demand.

Amazon’s ambition to covet the food retail industry has long existed, but because of transportation problems and food preservation problems, Amazon’s previous efforts ended in failure. The acquisition of Total Foods is a new opportunity for Amazon. Thanks to the complete supply chain of Whole Foods, Amazon can greatly reduce the supply risk and provide various food products for online customers. Of course, there will be some bad situations, for example, some ham and cheese can not be sold online; But this is just as well. Amazon will choose to significantly reduce the prices of these products in physical stores to clean up the inventory.

The addition of the whole food will also make more new scenes in the interaction between users and Alexa, such as:

　"Hey, Alexa, I want a gallon of milk, a loaf of bread, two barrels of yogurt and a jar of peanut butter. In addition, my recipe also includes pizza crust, ketchup and pepperoni. Please add these to my shopping cart! "

Similar scenes can lead to more possibilities. A realistic and reasonable imagination is that Amazon uses AI to recommend many dishes for you according to your favorites, and you are responsible for checking the dishes tonight, while Amazon will automatically place an order for you. Buy ingredients. What do you think? Is it interesting?

Now you can see why the market value of major supermarket chains evaporated by $13 billion after the acquisition was completed …

5. Amazon Prime: the second video service platform in the world; The sixth music streaming media service platform in the world

　The last of Amazon’s five pillars business is a bit complicated. On the one hand, Amazon Prime provides free 2-day delivery service in the United States, on the other hand, it is a streaming media entertainment content platform.

This is an excellent "flywheel connector". Research shows that the average spending of Prime customers is twice that of non-members.($1,300 vs $700)But if Amazon decides to reduce the membership fee to $7.99/month, they may earn more.

The reason lies in Prime Music and Prime Video. Both of these services provide unlimited free streaming services, which enable all authorized and original content of Amazon to compete directly with services such as Spotify and Netflix.

Although there is less original content on the Prime platform at present, and the quantity is less than those of Amazon’s competitors, the key point is-free. As we all know, free services can firmly bind users to Amazon’s product ecosystem.

If you can get 2-day free mail service without using Netflix and Spotify, I guess you will definitely check more products.

It is estimated that there are currently 63 million families in the United States who are Prime members, accounting for about 35% of the total population. Prime service increased Amazon’s recurring revenue by $1.9 billion in the first quarter of 2017, and doubled the purchase volume of almost every household-but this is not enough. For the number of members, Amazon’s principle is only four words: the more the better.

Amazon has "five pillars of business", any of which is enough to stand tall.

But the story is not over yet, and Amazon still has broad future development opportunities.

Amazon’s growth opportunities

Looking ahead, Amazon’s strong leadership and foresight are enough to make them invincible in the competition. The five main businesses all have great development potential and will usher in strong growth in the future.

However, Amazon is not satisfied with this. They are investing heavily in the next potential opportunity. Let’s take a look at them one by one:

1. Expand the market territory of Amazon Besi.

As mentioned above, Amazon Besi is the ultimate answer of Amazon Empire. Control the end-to-end service and you win everything. At present, although Amazon has invested a lot of resources in this business, they still have a long way to go.

As of December 14, 2017, Amazon Besi had 1,500 products.(300 models in 2013)However, with reference to the 480 million products of Amazon official website, the improvement space of Amazon Basics is full of imagination.

2. divest AWS business

I have always believed that Amazon is on the cusp of regulation. Although unlike Facebook, Google and Twitter, it is often at the forefront of public opinion, Amazon has approached the red line of supervision in many fields, naturally because of alleged monopoly.

As people and legislators gradually deepen their understanding of the Internet industry, it is only a matter of time before relevant departments get involved in Amazon. Prior to this, Amazon should pre-empt the AWS cloud service and stay away from the attention of antitrust agencies. After all, AWS is the only one of Amazon’s five branches that does not focus on business and logistics; This business is also the most suitable for independent development among the "five pillars".

Once the business divestiture is completed, the possibility of government intervention will be greatly reduced. What’s more, we all know that no matter what Amazon does, its share price will rise. Therefore, it can be predicted that the total market value of the new company and Amazon parent company after AWS independence is likely to exceed the current figure of 604 billion US dollars.

3. Expand the offline retail industry

Amazon seems to have made up its mind to build an offline physical retail store. Although the one-click online shopping model has made them earn a lot of money, they are also very aware of the importance of offline shopping experience. Some people think that once the physical retail store is completed, Amazon.com will become an important hub for users’ offline conversion rate and sales promotion; And Amazon’s offline stores will in turn boost the turnover of Amazon official website.

I basically agree with this statement. After all, Americans really like to try on clothes in offline stores. In my previous article, I also mentioned that if you really want to build a physical store, then the goods in the store must have at least one of the following two characteristics:

4. Increase the proportion of video content

Have you seen The Big Sick? This is a movie made by Amazon Studio, and the producer is Kumail Nanjiani. For a long time, I thought it was one of the most wonderful movies I have ever seen.

In 2017, Amazon spent $4.5 billion on original content. They saw the defeat of Netflix(market value of 90.57 billion US dollars)Hope, and the weapon is the original video program on Prime Video. Yes, Amazon has realized that streaming media is the future of video entertainment content.

As Amazon constantly updates its own video library, their evergreen content will not only please old customers, but also continuously contribute new members to Amazon Prime.

In a content(attention)For the king’s world, Amazon has successfully owned users’ hearts, brains and wallets.

5. Pay attention to the food industry

After winning Whole Foods Supermarket for $13 billion, the market value of American grocery industry reached $800 billion, which is six times that of Amazon’s global sales.

This contrast is obviously meaningful. However, if Amazon wants to succeed in this vast market, it must concentrate on properly allocating resources. I believe that if the decision is correct, Amazon has the opportunity to quadruple its sales in the next few years.

6. March into the pharmaceutical industry

The pharmaceutical industry is a big business in the United States, and Amazon certainly knows it. It is reported that Amazon’s actions in the pharmaceutical industry have aroused the concerns of major pharmaceutical companies such as CVS and Walgreens.

It is estimated that by 2021, the US prescription drug market will reach $610 billion. This market is close to the food retail industry. Considering that Amazon has the best logistics system in the world, if they choose to enter the pharmaceutical industry, it will be as easy as taking a walk in a nearby park.

Once there are generic drugs of Amazon brand, how many consumers will go to those inconvenient and expensive pharmacies?

It’s time to push some pills.

Other elements to consider.

I wrote in my previous article about how technology giants beat start-ups in the way they are best at; As I mentioned before, Amazon is definitely an expert in this respect: few companies are as ready to deal with all kinds of subversive changes as they are.

leadership

Amazon is one of the best managed companies in the world.

There are many reasons for this conclusion. Amazon follows a result-oriented corporate culture and encourages employees to take risks. The company pays attention to consumers, welcomes constructive criticism, and its employees have a sense of ownership.

Of course, you may think that the above words are exaggerated, but if you have a chance to observe them carefully, you will find that Amazon is really practicing the rules they have made.

Besides, Jeff Bezos did some other things. One of the most important things is the emphasis on commitment. Bezos requires employees to be firm and have strong mobility.

As you can see, whether it is the acquisition of Whole Foods or the announcement of its entry into the pharmaceutical industry, Amazon can gain immediate market recognition in almost every action. In the eyes of the public, Bezos has never missed it.

The ruthless, safe and reliable image carefully created by Bezos allows Amazon to transcend the temptation of short-term profits and always leave enough room for future development.

Of course, this also allows Bezos himself to hold a 17% stake in the company and become a veritable helm of this huge ship.

automation

Have you seen Amazon’s warehouse? If not, I suggest you watch the relevant videos.

The operational efficiency and automation level of Amazon warehouse are unmatched by others. Here, everything will be accurately measured, which enables them to try their best to reduce costs while still ensuring the high quality of products. In the case of large-scale production, this means higher unit economic benefits.

artificial intelligence

I just want to say: Amazon has the best AI experts in the world.

Whether it’s those guys who study Alexa, engineers who do millions of A/B experiments every day, or experts who focus on product recommendation system … Let’s just say that in terms of data processing ability and machine learning, the only one that can compete with Amazon is Google.

strategic acquisitions

Although Amazon has become the world’s top technology company.(if not the best in the world)However, their bank accounts are slightly smaller than those of other competitors in the industry: $22 billion in deposits prevents Amazon from making aggressive acquisitions.

However, after the acquisition of Total Foods last year, Amazon’s stock soared by 32%. This fully demonstrates the market’s trust in Bezos. Based on this reality, if Amazon decides to invest this $22 billion for a strategic acquisitions in the future, the market is likely to give positive feedback again.

Here are six areas where Amazon may make strategic investments:

1. Video industry

As a result, Amazon has invested more and more in Prime Video, and the competition with Netflix has become more and more fierce. The acquisition of a video production company is in line with business logic for Amazon, and there are many potential candidates who meet the standards.

At present, Amazon seems to be unable to afford Netflix. However, if this acquisition really happens, the consequence will be to completely kill cable TV and make Amazon an entertainment content industry.(and other related industries)The czar.

With Disney taking Hulu and time warner Inc. taking HBO, these two acquisitions are hopeless. If Amazon can win one of them before them, it will definitely be a huge victory.

Amazon’s most realistic goals at present should be the smaller film studios and the original video producers on YouTube. As we all know, YouTube is full of various and different styles of video content. If Amazon can attract all those video producers with different styles, then Prime Video can meet the needs of most users in terms of content.(You may even drag users on YouTube.)At the same time, the organic combination of long and short content will also hit Netflix and YouTube indiscriminately.

2. Music industry

Like video, Prime Music is also an important driving force for the expansion of Prime subscription service. Therefore, there is no doubt that investing in music is in line with the development plan of Amazon executives.

But unlike video, the price of buying a music company is lower, but the profit may be more considerable.

As the most commonly used music streaming service platform in the United States(I mean the free version)Pandora’s market value is only $1.33 billion. If it is acquired, Amazon will usher in a big change. The giant can make a big fuss between distribution and licensing agreement, and either one will give them more subscribers.

Another potential acquisition target is SoundCloud, a streaming music platform that is rumored to be bankrupt almost every few months. However, although they haven’t found a clear business realization idea, joining Amazon will be a win-win result for both parties.

Because SoundCloud is an interesting plug-and-play component, it fits well with Amazon’s existing platform foundation and user habits.

Up to now, SoundCloud has received $467 million in financing. However, it is not worth the price now. This affordable acquisition can reward investors and boost Amazon’s greater success.

Not only that, SoundCloud can also provide Amazon with the opportunity to enter the podcasting industry.(Another field with great potential).

3. Giant entity Shangchao

In stark contrast to the booming e-commerce industry, the traditional retail industry is increasingly depressed. However, if Amazon decides to enter the physical retail industry, then direct acquisition is obviously more cost-effective than self-built stores. The cooperation with Target will be a mutually beneficial cooperation, which is equivalent to a fatal blow to the common rival of the two companies-Wal-Mart.

Target has 1,828 branches in North America, although in Amazon’s view, these stores may be too big.(resulting in high maintenance cost)But this is not a big problem. Target’s distribution ability, storage space and sales ability are the key to attracting Amazon. Especially, considering the market value of Target is only $37.58 billion.(Only about 1/9 of Wal-Mart’s)Amazon can afford such an acquisition.

Add another fact: Target’s old customers are also Amazon’s ideal customers..

4. Fashion industry enterprises

Amazon is expanding into the fashion industry. Different from many other products, clothes in the fashion industry are not only fit, but also glamorous.

It is precisely because of this that the significance of clothing stores lies not in function, but in feeling; The driving force of sales is not the clothes themselves, but the try-on experience. Putting on beautiful tops and tight jeans is the fundamental reason why people are willing to pay.

So, if Amazon decides not to buy a full-category retailer,(such as Target)Instead of focusing on the fashion industry itself, Nordstrom is a good choice. This luxury clothing store has 349 branches in North America, and its market value is only $8 billion, which is similar to that of Whole Foods.

In addition to Nordstrom, Kohl, Macy, J.C., and Penney can also be included in the shortlist.

Don’t forget Amazon Besi, their goal has always been to turn all good products into their own. Through such an acquisition, Amazon designers can get closer to customers and quickly iterate on fashion trends across the country.

Realistically speaking, Amazon’s fashion ambition is still difficult to see, but we might as well give them two years to see if this online shopping giant can also win a place in the fashion world..

5. "Wild Ace" shared travel

This seemingly wild idea is not wild at all. Considering the huge potential of the taxi industry and Uber, it is definitely an ideal choice to win Lyft now. Let me explain to you why:

At present, the unit economic benefit of carpooling business is not good. Because of the dual characteristics of localization and globalization at the same time, the war between taxi companies can occur in every city in the world, and in the end, it is difficult for both sides to make a profit.

But what about brand advertising? How much value will it bring to your brand if the advertisement in the taxi can attract passengers’ attention?

From this perspective, Lyft is likely to become Amazon’s "sales engine".

In South Africa, Uber drivers often put a screen in the car that can play advertisements, so as to bring higher customers to Uber. Amazon can also learn from this promotion form, whether by signing a cooperation agreement or direct acquisition, Amazon can make a fortune. By understanding the positioning information of passengers, Amazon can promote their Prime Music and Video services in the local area, and also promote the sales of the online shopping platform itself. In other words, Lyft can become Amazon’s "high value-added old driver".

In addition, Amazon can also increase the bet on the Prime service, so that members can get more discounts when using Lyft to take a taxi. This will not only further tap the potential of Lyft, but also increase the number of Prime users.

Even if you think that "car ownership is dead" and "driverless is the future", it will not affect Amazon’s income in this field. To be exact, the popularity of self-driving cars will give Amazon more space to plan and arrange passengers’ "car life".

6. The telecommunications giant of Wild Ace

Imagine what would happen if Amazon won the Sprint? I know it is the smallest compared with other telecom giants, but Rao, Sprint also has 50.4 million customers.

Another important message is that Amazon itself is a platform for many users to buy mobile phones. Think about it, if Amazon says that you can get a month’s free phone service on Sprint by buying a mobile phone on the platform.(or other attractive conditions)Guess how many people will be willing to "take the bait"?

Because you have free advertisements on your own platform.(I mean Whole Foods). Amazon can easily carry out mobile sales services.(After all, most retail stores have started to handle prepaid package business now.).

Sprint is currently valued at 22.76 billion, which Amazon can still afford. This acquisition will have a significant impact on the existing competitive landscape of the telecommunications industry. Considering Amazon’s consistent style-lowering prices and reducing profits-users are likely to flock to Sprint, which will certainly increase the added value of this acquisition and effectively attack competitors.

grade

In fact, it is difficult for me to give Amazon any score except A+, but considering some unstable factors of the company itself and the potential impact of decentralized blockchain start-ups,I think the grade A is more reasonable.

In fact, Amazon has only two weaknesses: one is the potential regulatory risk, and the other is the high operating cost. Although I haven’t mentioned the latter in this article, it is still a topic worth discussing.

As of now, Amazon still does not have it.(although it is close)Profit. And that’s why Bezos can’t get an A+ from me. Although the market is still saying that "it doesn’t matter whether it is profitable or not", we all know that the climate may change at any time. Once the capital market changes dramatically and Amazon is affected, their stocks are likely to be turbulent.

But even so, I am still optimistic about Amazon. Welcome the future monopolist, he is Mr. Jeff Bezos.

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Amazon is really a great enterprise.

This "five-headed dragon" occupies a dominant position in almost all his fields. Never go against Bezos, you won’t get good results.